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Macrophage-pathogen interactions in infectious diseases: new therapeutic insights from the zebrafish host model
Studying macrophage biology in the context of a whole living organism provides unique
possibilities to understand the contribution of this extremely dynamic cell subset in the …
possibilities to understand the contribution of this extremely dynamic cell subset in the …
[HTML][HTML] Toxin-antitoxin systems in clinical pathogens
Toxin-antitoxin (TA) systems are prevalent in bacteria and archaea. Although not essential
for normal cell growth, TA systems are implicated in multiple cellular functions associated …
for normal cell growth, TA systems are implicated in multiple cellular functions associated …
Biosynthesis of fragin is controlled by a novel quorum sensing signal
Members of the diazeniumdiolate class of natural compounds show potential for drug
development because of their antifungal, antibacterial, antiviral, and antitumor activities. Yet …
development because of their antifungal, antibacterial, antiviral, and antitumor activities. Yet …
[HTML][HTML] An evolutionary perspective on plasmid lifestyle modes
Highlights•Plasmid evolution reviewed from the perspective of plasmids.•Mobility, stability,
and indispensability largely determine plasmid lifestyles.•Changes in plasmid traits facilitate …
and indispensability largely determine plasmid lifestyles.•Changes in plasmid traits facilitate …
The genome analysis of Candidatus Burkholderia crenata reveals that secondary metabolism may be a key function of the Ardisia crenata leaf nodule symbiosis
A Carlier, L Fehr, M Pinto‐Carbó… - Environmental …, 2016 - Wiley Online Library
A majority of A rdisia species harbour B urkholderia sp. bacteria within specialized leaf
nodules. The bacteria are transmitted hereditarily and have not yet been cultured outside of …
nodules. The bacteria are transmitted hereditarily and have not yet been cultured outside of …
Chromids Aid Genome Expansion and Functional Diversification in the Family Burkholderiaceae
Multipartite genomes, containing at least two large replicons, are found in diverse bacteria;
however, the advantage of this genome structure remains incompletely understood. Here …
however, the advantage of this genome structure remains incompletely understood. Here …
A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis
A O'Connor, I Jurado‐Martín, MM Mysior… - …, 2023 - Wiley Online Library
Universal stress proteins (USPs) are ubiquitously expressed in bacteria, archaea, and
eukaryotes and play a lead role in adaptation to environmental conditions. They enable …
eukaryotes and play a lead role in adaptation to environmental conditions. They enable …
Transposon sequencing reveals the essential gene set and genes enabling gut symbiosis in the insect symbiont Caballeronia insecticola
R Jouan, G Lextrait, J Lachat, A Yokota… - ISME …, 2024 - academic.oup.com
Caballeronia insecticola is a bacterium belonging to the Burkholderia genus sensu lato,
which is able to colonize multiple environments like soils and the gut of the bean bug …
which is able to colonize multiple environments like soils and the gut of the bean bug …
Insights into the diverse roles of the terminal oxidases in Burkholderia cenocepacia H111
S Paszti, O Biner, Y Liu, K Bolli, SD Jeggli, G Pessi… - Scientific Reports, 2025 - nature.com
Burkholderia cenocepacia H111 is an obligate aerobic bacterium which has been isolated
from a cystic fibrosis (CF) patient. In CF lungs the environment is considered micro-oxic or …
from a cystic fibrosis (CF) patient. In CF lungs the environment is considered micro-oxic or …
Independent origins and evolution of the secondary replicons of the class Gammaproteobacteria
Multipartite genomes, consisting of more than one replicon, have been found in
approximately 10% of bacteria, many of which belong to the phylum Proteobacteria. Many …
approximately 10% of bacteria, many of which belong to the phylum Proteobacteria. Many …