Macrophage-pathogen interactions in infectious diseases: new therapeutic insights from the zebrafish host model

V Torraca, S Masud, HP Spaink… - Disease models & …, 2014 - journals.biologists.com
Studying macrophage biology in the context of a whole living organism provides unique
possibilities to understand the contribution of this extremely dynamic cell subset in the …

[HTML][HTML] Toxin-antitoxin systems in clinical pathogens

L Fernández-García, L Blasco, M Lopez, G Bou… - Toxins, 2016 - mdpi.com
Toxin-antitoxin (TA) systems are prevalent in bacteria and archaea. Although not essential
for normal cell growth, TA systems are implicated in multiple cellular functions associated …

Biosynthesis of fragin is controlled by a novel quorum sensing signal

C Jenul, S Sieber, C Daeppen, A Mathew… - Nature …, 2018 - nature.com
Members of the diazeniumdiolate class of natural compounds show potential for drug
development because of their antifungal, antibacterial, antiviral, and antitumor activities. Yet …

[HTML][HTML] An evolutionary perspective on plasmid lifestyle modes

N Hülter, J Ilhan, T Wein, AS Kadibalban… - Current opinion in …, 2017 - Elsevier
Highlights•Plasmid evolution reviewed from the perspective of plasmids.•Mobility, stability,
and indispensability largely determine plasmid lifestyles.•Changes in plasmid traits facilitate …

The genome analysis of Candidatus Burkholderia crenata reveals that secondary metabolism may be a key function of the Ardisia crenata leaf nodule symbiosis

A Carlier, L Fehr, M Pinto‐Carbó… - Environmental …, 2016 - Wiley Online Library
A majority of A rdisia species harbour B urkholderia sp. bacteria within specialized leaf
nodules. The bacteria are transmitted hereditarily and have not yet been cultured outside of …

Chromids Aid Genome Expansion and Functional Diversification in the Family Burkholderiaceae

GC Dicenzo, A Mengoni, E Perrin - Molecular biology and …, 2019 - academic.oup.com
Multipartite genomes, containing at least two large replicons, are found in diverse bacteria;
however, the advantage of this genome structure remains incompletely understood. Here …

A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis

A O'Connor, I Jurado‐Martín, MM Mysior… - …, 2023 - Wiley Online Library
Universal stress proteins (USPs) are ubiquitously expressed in bacteria, archaea, and
eukaryotes and play a lead role in adaptation to environmental conditions. They enable …

Transposon sequencing reveals the essential gene set and genes enabling gut symbiosis in the insect symbiont Caballeronia insecticola

R Jouan, G Lextrait, J Lachat, A Yokota… - ISME …, 2024 - academic.oup.com
Caballeronia insecticola is a bacterium belonging to the Burkholderia genus sensu lato,
which is able to colonize multiple environments like soils and the gut of the bean bug …

Insights into the diverse roles of the terminal oxidases in Burkholderia cenocepacia H111

S Paszti, O Biner, Y Liu, K Bolli, SD Jeggli, G Pessi… - Scientific Reports, 2025 - nature.com
Burkholderia cenocepacia H111 is an obligate aerobic bacterium which has been isolated
from a cystic fibrosis (CF) patient. In CF lungs the environment is considered micro-oxic or …

Independent origins and evolution of the secondary replicons of the class Gammaproteobacteria

C Riccardi, P Koper, G Innocenti… - Microbial …, 2023 - microbiologyresearch.org
Multipartite genomes, consisting of more than one replicon, have been found in
approximately 10% of bacteria, many of which belong to the phylum Proteobacteria. Many …