Malaria parasites avoid immune clearance through their ability to systematically alter
antigens exposed on the surface of infected red blood cells. This is accomplished by tightly …

The most severe form of malaria, caused by infection with Plasmodium falciparum parasites,
continues to be an important cause of human suffering and poverty. The P. falciparum …

Abstract Background The malaria parasite Plasmodium falciparum has an unusually
euchromatic genome with poorly conserved positioning of nucleosomes in intergenic …

Most studies of genome organization have focused on intrachromosomal (cis) contacts
because they harbor key features such as DNA loops and topologically associating …

The Plasmodium falciparum alternative histones Pf H2A. Z and Pf H2B. Z are enriched in the
same nucleosomes in intergenic euchromatin but depleted from heterochromatin. They …

Epigenetic regulation is a critical mechanism in controlling virulence, differentiation, and
survival of the human malaria parasite Plasmodium (P.) falciparum. Bromodomain proteins …

Controlled human malaria infections (CHMI) are a valuable tool to study parasite gene
expression in vivo under defined conditions. In previous studies, virulence gene expression …

Most studies of genome organization have focused on intra-chromosomal (cis) contacts
because they harbor key features such as DNA loops and topologically associating …

Eukaryotic, unicellular parasites of the Plasmodium genus are the causative agents of
malaria. During their life cycle, these parasites alternate between a vertebrate and an insect …

The rapid development of DNA sequencing technologies has opened up new avenues of
research, including the investigation of population structure within infectious diseases (both …