Imaging reveals complex structures and dynamic interactive processes, located deep inside
the body, that are otherwise difficult to decipher. Numerous imaging modalities harness …

Immunological studies of single proteins in a single cell type have been complemented in
recent years by larger studies, enabled by emerging high-throughput technologies. This …

Itch is an evolutionarily conserved sensation that facilitates expulsion of pathogens and
noxious stimuli from the skin. However, in organ failure, cancer, and chronic inflammatory …

Background Given the strong environmental influence on both epigenetic marks and allergic
asthma in children, the epigenetic alterations in respiratory epithelia might provide insight …

As treatment of the early, inflammatory phase of sepsis improves, post-sepsis
immunosuppression and secondary infection have increased in importance. How early …

Hundreds of immune cell types work in coordination to maintain tissue homeostasis. Upon
infection, dramatic changes occur with the localization, migration, and proliferation of the …

Allergic diseases are complex diseases caused by a combination of genetic and
environmental factors. To determine the genetic components of these diseases and to …

The move toward precision medicine has highlighted the importance of understanding
biological variability within and across individuals in the human population. In particular …

Understanding how drugs affect the immune system has consequences for treating disease
and minimizing unwanted side effects. Here we present an integrative computational …

Micro RNA s (mi RNA s) have emerged as important regulators of gene expression in
diverse biological processes ranging from cell proliferation and survival to organ …