Lipids, inflammasomes, metabolism, and disease

PK Anand - Immunological Reviews, 2020 - Wiley Online Library
Inflammasomes are multi‐protein complexes that regulate the cleavage of cysteine protease
caspase‐1, secretion of inflammatory cytokines, and induction of inflammatory cell death …

[HTML][HTML] The impact of curcumin on migraine: a comprehensive review

H Heidari, M Shojaei, G Askari, M Majeed… - Biomedicine & …, 2023 - Elsevier
Migraine, a neurovascular condition, is a chronic and lifelong disease that affects about 15%
of the population worldwide. Although the exact pathophysiology and etiology of migraine …

The effects of diosgenin on hypolipidemia and its underlying mechanism: a review

F Sun, X Yang, C Ma, S Zhang, L Yu, H Lu… - Diabetes, Metabolic …, 2021 - Taylor & Francis
Hyperlipidemia is a disorder of lipid metabolism, which is a major cause of coronary heart
disease. Although there has been considerable progress in hyperlipidemia treatment …

Medicinal plants and bioactive natural products as inhibitors of NLRP3 inflammasome

M Bagherniya, H Khedmatgozar… - Phytotherapy …, 2021 - Wiley Online Library
The NLR family, pyrin domain‐containing 3 (NLRP3) inflammasome is a multiprotein
complex that induces caspase‐1 activation and the downstream substrates involved with the …

Natural products targeting inflammation-related metabolic disorders: A comprehensive review

F Nainu, A Frediansyah, SS Mamada, AD Permana… - Heliyon, 2023 - cell.com
Currently, the incidence of metabolic disorders is increasing, setting a challenge to global
health. With major advancement in the diagnostic tools and clinical procedures, much has …

The effects of medicinal plants and bioactive natural compounds on homocysteine

MA Atazadegan, M Bagherniya, G Askari, A Tasbandi… - Molecules, 2021 - mdpi.com
Background: Among non-communicable diseases, cardiovascular diseases (CVDs) are the
leading cause of mortality and morbidity in global communities. By 2030, CVD-related …

[HTML][HTML] Berberine: Ins and outs of a nature-made PCSK9 inhibitor

S Ataei, P Kesharwani, A Sahebkar - EXCLI journal, 2022 - ncbi.nlm.nih.gov
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secreted protein and a critical
regulator of low-density lipoprotein-cholesterol (LDL-C) through inducing degradation of the …

The effect of medicinal plants on cirrhosis: A systematic review of clinical trials

S Amini, M Bagherniya, AE Butler… - Phytotherapy …, 2023 - Wiley Online Library
Medicinal plants with minimal side effects, low cost, and liver‐protective effects can be a
suitable treatment option for cirrhosis. Therefore, this systematic review aimed to determine …

Hypocholesterolemic efficacy of secoisolariciresinol diglucoside and its polymer in rat

Y Guo, X Yang, TJ Tse, SK Purdy… - Journal of Natural …, 2021 - ACS Publications
Hypercholesterolemia is a risk factor for cardiovascular disease. Conventional treatment
methods include lifestyle changes and pharmaceutical interventions, but recently Health …

Effect of curcumin on glycemic control in patients with type 2 diabetes: a systematic review of randomized clinical trials

A Mahdavi, S Moradi, G Askari, B Iraj… - Studies on Biomarkers …, 2021 - Springer
Type 2 diabetes mellitus (T2DM) is a chronic metabolic condition, which carries
considerable morbidity and mortality. There is growing evidence that curcumin could …