Ceramic materials for biomedical applications: an overview on properties and fabrication processes

L Vaiani, A Boccaccio, AE Uva, G Palumbo… - Journal of Functional …, 2023 - mdpi.com
A growing interest in creating advanced biomaterials with specific physical and chemical
properties is currently being observed. These high-standard materials must be capable to …

Shape/properties collaborative intelligent manufacturing of artificial bone scaffold: structural design and additive manufacturing process

P Feng, L Liu, F Yang, R Min, P Wu, C Shuai - Biofabrication, 2024 - iopscience.iop.org
Artificial bone graft stands out for avoiding limited source of autograft as well as susceptibility
to infection of allograft, which makes it a current research hotspot in the field of bone defect …

Design and properties of biomimetic irregular scaffolds for bone tissue engineering

H Chen, Y Liu, C Wang, A Zhang, B Chen… - Computers in Biology …, 2021 - Elsevier
The treatment of sizeable segmental bone defects remains a challenge encountered by
surgeons. In addition to bone transplantation, porous scaffolds have become a common …

Optimal mechanical properties of Hydroxyapatite gradient Voronoi porous scaffolds for bone applications—A numerical study

M Rezapourian, I Hussainova - Journal of the Mechanical Behavior of …, 2023 - Elsevier
Irregular Voronoi-based lattice (IVL) structures in tissue engineering (TE) have significant
potential for bone regeneration. These scaffolds can mimic natural human bone …

A morphological, topological and mechanical investigation of gyroid, spinodoid and dual-lattice algorithms as structural models of trabecular bone

M Vafaeefar, KM Moerman, M Kavousi… - Journal of the Mechanical …, 2023 - Elsevier
In this study, we evaluate the performance of three algorithms as computational models of
trabecular bone architecture, through systematic evaluation of morphometric, topological …

Structural and topological design of conformal bilayered scaffolds for bone tissue engineering

L Vaiani, AE Uva, A Boccaccio - Thin-Walled Structures, 2023 - Elsevier
A fundamental outcome of bone tissue engineering is the regeneration of bone defects
presenting large dimensions. A promising solution in biomedical practice is the implantation …

Initial mechanical conditions within an optimized bone scaffold do not ensure bone regeneration – an in silico analysis

C Perier-Metz, GN Duda, S Checa - Biomechanics and Modeling in …, 2021 - Springer
Large bone defects remain a clinical challenge because they do not heal spontaneously. 3-
D printed scaffolds are a promising treatment option for such critical defects. Recent scaffold …

Exploring macroporosity of additively manufactured titanium metamaterials for bone regeneration with quality by design: A systematic literature review

D Martinez-Marquez, Y Delmar, S Sun, RA Stewart - Materials, 2020 - mdpi.com
Additive manufacturing facilitates the design of porous metal implants with detailed internal
architecture. A rationally designed porous structure can provide to biocompatible titanium …

Mechanobiological approach to design and optimize bone tissue scaffolds 3D printed with fused deposition modeling: A feasibility study

G Percoco, AE Uva, M Fiorentino, M Gattullo… - Materials, 2020 - mdpi.com
In spite of the rather large use of the fused deposition modeling (FDM) technique for the
fabrication of scaffolds, no studies are reported in the literature that optimize the geometry of …

[HTML][HTML] A mechano-regulation model to design and optimize the surface microgeometry of titanium textured devices for biomedical applications

A Boccaccio - Journal of the Mechanical Behavior of Biomedical …, 2024 - Elsevier
In a technological context where, thanks to the additive manufacturing techniques, even
sophisticated geometries as well as surfaces with specific micrometric features can be …