Parasitic helminths have coevolved with humans over millennia, intricately refining and
develo** an array of mechanisms to suppress or skew the host's immune system, thereby …

Schistosomiasis causes significant levels of morbidity and mortality in many geographical
regions of the world. The disease is caused by infections with parasitic blood flukes known …

Schistosomiasis, caused mainly by S. mansoni, S. haematobium and S. japonicum,
continues to be a serious tropical disease and public health problem resulting in an …

The development of a vaccine for Fasciola spp. in livestock is a challenge and would be
advanced by harnessing our knowledge of acquired immune mechanisms expressed by …

Schistosomiasis, caused by human trematode blood flukes (schistosomes), remains one of
the most prevalent and serious of the neglected tropical parasitic diseases. Currently …

The immune system is a network of specialized cell types and tissues that communicates via
cytokines and direct contact, to orchestrate specific types of defensive responses. Until …

Several candidate human schistosomiasis vaccines are in different stages of preclinical and
clinical development. The major targets are Schistosoma haematobium (urogenitial …

Eukaryotic parasites and pathogens continue to cause some of the most detrimental and
difficult to treat diseases (or disease states) in both humans and animals, while also …