The family of nuclear factor-kappaB (NF-κB) transcription factors is intimately involved in the
regulation of expression of numerous genes in the setting of the inflammatory response …

Background Osteoarthritis (OA) is a common form of arthritis and is often associated with
significant disability and impaired quality of life. This is an update of a Cochrane review first …

Osteoarthritis (OA) is a prevalent degenerative disease that afflicts more than 250 million
people worldwide, impairing their mobility and quality of life. However, conventional drug …

Osteoarthritis (OA) is the most common disabling joint disease throughout the world and its
therapeutic effect is still not satisfactory in clinic nowadays. Recent studies showed that the …

Osteoarthritis (OA) is the most common disabling joint disease with no effective disease
modifying drugs. Extracellular vesicles released by several types of mesenchymal stem cells …

Background: Platelet-rich plasma (PRP) has recently been postulated as a treatment for
osteoarthritis (OA). Although anabolic effects of PRP on chondrocytes are well documented …

Nanozymes are widely applied for treating various major diseases, including neurological
diseases and tumors. However, the biodegradability of nanozymes remains a great …

Background Safflower yellow (SY) is the main active ingredient of safflower, with various
pharmacological effects such as anticoagulating, antioxidant, and anti-arthritis effects …

With osteoarthritis being the most common degenerative disease in pet animals, a very
broad panel of natural health products is available on the market for its management. The …

Pro-inflammatory cytokines such as interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-
α) play a key role in the pathogenesis of osteoarthritis (OA). Anti-inflammatory agents …