Pathogenesis, epidemiology and control of Group A Streptococcus infection
S Brouwer, T Rivera-Hernandez, BF Curren… - Nature Reviews …, 2023 - nature.com
Abstract Streptococcus pyogenes (Group A Streptococcus; GAS) is exquisitely adapted to
the human host, resulting in asymptomatic infection, pharyngitis, pyoderma, scarlet fever or …
the human host, resulting in asymptomatic infection, pharyngitis, pyoderma, scarlet fever or …
Acute rheumatic fever and rheumatic heart disease
Acute rheumatic fever (ARF) is the result of an autoimmune response to pharyngitis caused
by infection with group A Streptococcus. The long-term damage to cardiac valves caused by …
by infection with group A Streptococcus. The long-term damage to cardiac valves caused by …
Disease manifestations and pathogenic mechanisms of group A Streptococcus
Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …
infections such as pharyngitis and impetigo and serious infections such as necrotizing …
Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells
Congenital Zika syndrome (CZS) causes early brain development impairment by affecting
neural progenitor cells (NPCs). Here, we analyze NPCs from three pairs of dizygotic twins …
neural progenitor cells (NPCs). Here, we analyze NPCs from three pairs of dizygotic twins …
Post-infectious group A streptococcal autoimmune syndromes and the heart
WJ Martin, AC Steer, PR Smeesters, J Keeble… - Autoimmunity …, 2015 - Elsevier
There is a pressing need to reduce the high global disease burden of rheumatic heart
disease (RHD) and its harbinger, acute rheumatic fever (ARF). ARF is a classical example of …
disease (RHD) and its harbinger, acute rheumatic fever (ARF). ARF is a classical example of …
Rheumatic heart disease: a review of the current status of global research activity
Rheumatic heart disease (RHD) is a serious and long-term consequence of acute rheumatic
fever (ARF), an autoimmune sequela of a mucosal infection by Streptococcus pyogenes …
fever (ARF), an autoimmune sequela of a mucosal infection by Streptococcus pyogenes …
Emerging importance of chemokine receptor CXCR3 and its ligands in cardiovascular diseases
The CXC chemokines, CXCL4,-9,-10,-11, CXCL4L1, and the CC chemokine CCL21,
activate CXC chemokine receptor 3 (CXCR3), a cell-surface G protein-coupled receptor …
activate CXC chemokine receptor 3 (CXCR3), a cell-surface G protein-coupled receptor …
Effects of anti-integrin treatment with vedolizumab on immune pathways and cytokines in inflammatory bowel diseases
Background and aims Despite proven clinical efficacy of vedolizumab (VDZ) for inducing
and maintaining remission in patients with Crohn's disease (CD) and ulcerative colitis (UC) …
and maintaining remission in patients with Crohn's disease (CD) and ulcerative colitis (UC) …
Cytokine imbalance in acute rheumatic fever and rheumatic heart disease: Mechanisms and therapeutic implications
Abstract Acute Rheumatic Fever (ARF) and Rheumatic Heart Disease (RHD) are
autoimmune sequelae of Group A Streptococcus infection with significant global disease …
autoimmune sequelae of Group A Streptococcus infection with significant global disease …
Rheumatic Heart Disease: Molecules Involved in Valve Tissue Inflammation Leading to the Autoimmune Process and Anti-S. pyogenes Vaccine
The major events leading to both rheumatic fever (RF) and rheumatic heart disease (RHD)
are reviewed. Several genes are involved in the development of RF and RHD. The …
are reviewed. Several genes are involved in the development of RF and RHD. The …