Endometrial carcinoma: molecular subtypes, precursors and the role of pathology in early diagnosis

J Huvila, J Pors, EF Thompson… - The Journal of …, 2021 - Wiley Online Library
Endometrial carcinoma (EC) is classified into a wide range of morphological variants; this list
has expanded over the past decade with the inclusion of mesonephric‐like and …

Molecular approaches for classifying endometrial carcinoma

JM Piulats, E Guerra, M Gil-Martín, B Roman-Canal… - Gynecologic …, 2017 - Elsevier
Endometrial carcinoma is the most common cancer of the female genital tract. This review
article discusses the usefulness of molecular techniques to classify endometrial carcinoma …

The genetic landscape of endometrial clear cell carcinomas

DF DeLair, KA Burke, P Selenica, RS Lim… - The Journal of …, 2017 - Wiley Online Library
Clear cell carcinoma of the endometrium is a rare type of endometrial cancer that is
generally associated with an aggressive clinical behaviour. Here, we sought to define the …

High-grade endometrial carcinomas: morphologic and immunohistochemical features, diagnostic challenges and recommendations

R Murali, B Davidson, O Fadare… - International Journal …, 2019 - journals.lww.com
This review of challenging diagnostic issues concerning high-grade endometrial carcinomas
is derived from the authors' review of the literature followed by discussions at the …

Clinicopathologic and Genomic Analysis of TP53-Mutated Endometrial Carcinomas

A Momeni-Boroujeni, W Dahoud, CM Vanderbilt… - Clinical Cancer …, 2021 - AACR
Purpose: Copy number–high endometrial carcinomas were described by The Cancer
Genome Atlas as high-grade endometrioid and serous cancers showing frequent copy …

Targeted mutation analysis of endometrial clear cell carcinoma

LN Hoang, MK McConechy, B Meng… - …, 2015 - Wiley Online Library
Aims Endometrial clear cell carcinomas (CCC) constitute fewer than 5% of all carcinomas of
the endometrium. Currently, little is known regarding the genetic basis of endometrial CCC …

Frequent expression of napsin A in clear cell carcinoma of the endometrium: potential diagnostic utility

O Fadare, MM Desouki, K Gwin… - The American journal …, 2014 - journals.lww.com
The histoty** of high-grade endometrial carcinomas with clear cells may be subject to
significant interobserver variability, which suggests that a biomarker that can distinguish …

[HTML][HTML] Mismatch repair status and PD-L1 expression in clear cell carcinomas of the ovary and endometrium

BC Willis, EA Sloan, KA Atkins, MH Stoler, AM Mills - Modern Pathology, 2017 - Elsevier
Clear cell carcinoma represents a distinct histologic type of müllerian carcinoma that is
resistant to conventional chemotherapy. Expression of programmed cell death ligand (PD …

Clear cell carcinoma of the endometrium: an immunohistochemical and molecular analysis of 45 cases

GF Zannoni, A Santoro, G Angelico, S Spadola… - Human Pathology, 2019 - Elsevier
The aim of the present paper is to study a cohort of pure selected endometrial clear cell
carcinomas (ECCCs) from an immunohistochemical and molecular perspective to provide …

Napsin A is frequently expressed in clear cell carcinoma of the ovary and endometrium

M Iwamoto, Y Nakatani, K Fugo, T Kishimoto… - Human Pathology, 2015 - Elsevier
Napsin A is a reliable marker for pulmonary adenocarcinoma and is expressed in a subset
of ovarian clear cell carcinomas (O-CCCs), endometrial (EM) CCCs, and endometrioid …