Effects of pulsed, spatially fractionated, microscopic synchrotron X-ray beams on normal and tumoral brain tissue

E Bräuer-Krisch, R Serduc, EA Siegbahn… - … Research/Reviews in …, 2010 - Elsevier
Microbeam radiation therapy (MRT) uses highly collimated, quasi-parallel arrays of X-ray
microbeams of 50–600keV, produced by third generation synchrotron sources, such as the …

[HTML][HTML] Medical physics aspects of the synchrotron radiation therapies: Microbeam radiation therapy (MRT) and synchrotron stereotactic radiotherapy (SSRT)

E Bräuer-Krisch, JF Adam, E Alagoz, S Bartzsch… - Physica Medica, 2015 - Elsevier
Abstract Stereotactic Synchrotron Radiotherapy (SSRT) and Microbeam Radiation Therapy
(MRT) are both novel approaches to treat brain tumor and potentially other tumors using …

Interlaced x-ray microplanar beams: a radiosurgery approach with clinical potential

FA Dilmanian, Z Zhong, T Bacarian… - Proceedings of the …, 2006 - National Acad Sciences
Studies have shown that x-rays delivered as arrays of parallel microplanar beams
(microbeams), 25-to 90-μm thick and spaced 100–300 μm on-center, respectively, spare …

[HTML][HTML] Tissue-sparing effect of x-ray microplanar beams particularly in the CNS: is a bystander effect involved?

FA Dilmanian, Y Qu, LE Feinendegen, LA Peña… - Experimental …, 2007 - Elsevier
OBJECTIVE: Normal tissues, including the central nervous system, tolerate single exposures
to narrow planes of synchrotron-generated x-rays (microplanar beams; microbeams) up to …

Determination of dosimetrical quantities used in microbeam radiation therapy (MRT) with Monte Carlo simulations

EA Siegbahn, J Stepanek, E Bräuer‐Krisch… - Medical …, 2006 - Wiley Online Library
Microbeam radiation therapy (MRT) is being performed by using an array of narrow
rectangular x‐ray beams (typical beam sizes), positioned close to each other (typically …

Technical advances in x-ray microbeam radiation therapy

S Bartzsch, S Corde, JC Crosbie, L Day… - Physics in Medicine …, 2020 - iopscience.iop.org
In the last 25 years microbeam radiation therapy (MRT) has emerged as a promising
alternative to conventional radiation therapy at large, third generation synchrotrons. In MRT …

Development and commissioning of a Monte Carlo photon beam model for the forthcoming clinical trials in microbeam radiation therapy

I Martínez‐Rovira, J Sempau, Y Prezado - Medical physics, 2012 - Wiley Online Library
Purpose: A new radiotherapy technique, named microbeam radiation therapy (MRT), is
under development at the ID17 Biomedical Beamline of the European Synchrotron …

Brain tumor vessel response to synchrotron microbeam radiation therapy: a short-term in vivo study

R Serduc, T Christen, J Laissue, R Farion… - Physics in Medicine …, 2008 - iopscience.iop.org
The aim of this work focuses on the description of the short-term response of a 9L brain
tumor model and its vasculature to microbeam radiation therapy (MRT) using magnetic …

A method of dosimetry for synchrotron microbeam radiation therapy using radiochromic films of different sensitivity

JC Crosbie, I Svalbe, SM Midgley, N Yagi… - Physics in Medicine …, 2008 - iopscience.iop.org
This paper describes a method of film dosimetry used to measure the peak-to-valley dose
ratios for synchrotron microbeam radiation therapy (MRT). Two types of radiochromic film …

Validation of a Monte Carlo simulation for microbeam radiation therapy on the imaging and medical beamline at the Australian Synchrotron

A Dipuglia, M Cameron, JA Davis, IM Cornelius… - Scientific Reports, 2019 - nature.com
Abstract Microbeam Radiation Therapy (MRT) is an emerging cancer treatment modality
characterised by the use of high-intensity synchrotron-generated x-rays, spatially …