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SARS-CoV-2 infects red blood cell progenitors and dysregulates hemoglobin and iron metabolism
R Kronstein-Wiedemann, M Stadtmüller… - Stem Cell Reviews and …, 2022 - Springer
Background SARS-CoV-2 infection causes acute respiratory distress, which may progress to
multiorgan failure and death. Severe COVID-19 disease is accompanied by reduced …
multiorgan failure and death. Severe COVID-19 disease is accompanied by reduced …
SARS-CoV-2-associated lymphopenia: possible mechanisms and the role of CD147
T lymphocytes play a primary role in the adaptive antiviral immunity. Both lymphocytosis and
lymphopenia were found to be associated with severe acute respiratory syndrome …
lymphopenia were found to be associated with severe acute respiratory syndrome …
Metabolomic and immune alterations in long COVID patients with chronic fatigue syndrome
Introduction A group of SARS-CoV-2 infected individuals present lingering symptoms,
defined as long COVID (LC), that may last months or years post the onset of acute disease …
defined as long COVID (LC), that may last months or years post the onset of acute disease …
[HTML][HTML] Diverse immunological dysregulation, chronic inflammation, and impaired erythropoiesis in long COVID patients with chronic fatigue syndrome
A substantial number of patients recovering from acute SARS-CoV-2 infection present
serious lingering symptoms, often referred to as long COVID (LC). However, a subset of …
serious lingering symptoms, often referred to as long COVID (LC). However, a subset of …
Galectin-9 promotes natural killer cells activity via interaction with CD44
Natural killer (NK) cells are a potent innate source of cytokines and cytoplasmic granules.
Their effector functions are tightly synchronized by the balance between the stimulatory and …
Their effector functions are tightly synchronized by the balance between the stimulatory and …
The quality of SARS-CoV-2–specific T cell functions differs in patients with mild/moderate versus severe disease, and T cells expressing coinhibitory receptors are …
Understanding the function of SARS-CoV-2 Ag-specific T cells is crucial for the monitoring of
antiviral immunity and vaccine design. Currently, both impaired and robust T cell immunity is …
antiviral immunity and vaccine design. Currently, both impaired and robust T cell immunity is …
[HTML][HTML] The role of CD71+ erythroid cells in the regulation of the immune response
Complex regulation of the immune response is necessary to support effective defense of an
organism against hostile invaders and to maintain tolerance to harmless microorganisms …
organism against hostile invaders and to maintain tolerance to harmless microorganisms …
[HTML][HTML] The role of acidosis in the pathogenesis of severe forms of COVID-19
YD Nechipurenko, DA Semyonov, IA Lavrinenko… - Biology, 2021 - mdpi.com
Simple Summary Recently, several studies have shown that acidosis, which is increased
acidity in the blood and other body tissues, is often associated with severe COVID-19. In this …
acidity in the blood and other body tissues, is often associated with severe COVID-19. In this …
Analysis of SARS-CoV-2 isolates, namely the Wuhan strain, Delta variant, and Omicron variant, identifies differential immune profiles
There is an urgent need to better understand the impact of different severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) variants on immune response and disease …
syndrome coronavirus 2 (SARS-CoV-2) variants on immune response and disease …
High–temporal resolution profiling reveals distinct immune trajectories following the first and second doses of COVID-19 mRNA vaccines
Knowledge of the mechanisms underpinning the development of protective immunity
conferred by mRNA vaccines is fragmentary. Here, we investigated responses to …
conferred by mRNA vaccines is fragmentary. Here, we investigated responses to …