HFIP in organic synthesis

HF Motiwala, AM Armaly, JG Cacioppo… - Chemical …, 2022 - ACS Publications
1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating
solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic …

Recent advancements in strategies for the synthesis of imidazoles, thiazoles, oxazoles, and benzimidazoles

K Kant, CK Patel, S Banerjee, P Naik, AK Atta… - …, 2023 - Wiley Online Library
Nitrogen‐containing heterocycles such as imidazoles, thiazoles, and oxazoles play a
significant role in the fields of biological and pharmaceutical chemistry. These compounds …

Visible-light-induced photocatalytic oxidative decarboxylation of cinnamic acids to 1, 2-diketones

S Chand, AK Pandey, R Singh… - The Journal of Organic …, 2021 - ACS Publications
Visible-Light-Induced Photocatalytic Oxidative Decarboxylation of Cinnamic Acids to 1,2-Diketones
| The Journal of Organic Chemistry Recently Viewedclose modal Pair your accounts. Export …

Sustainable approaches towards the synthesis of quinoxalines: An update

A Kumar, TM Dhameliya, K Sharma, KA Patel… - Journal of Molecular …, 2022 - Elsevier
Heterocycles and their derivatives have been inspiring medicinal chemists to device novel,
greener and efficient ways to synthesized them as the majority of drugs available in the …

HFIP‐Mediated Cyclodesulfurization Approach for the Synthesis of 2‐Aminobenzoxazole and 2‐Aminobenzothiazole Derivatives

K Kant, CK Patel, S Banerjee, P Naik… - Asian Journal of …, 2024 - Wiley Online Library
A straightforward strategy for the synthesis of pharmaceutically active 2‐aminobenzoxazoles
and 2‐aminobenzothiazoles is described by using 2‐aminophenols, 2‐aminothiophenols …

Transition-metal-free transfer hydrogenative cascade reaction of nitroarenes with amines/alcohols: redox-economical access to benzimidazoles

AK Kabi, R Gujjarappa, A Roy, A Sahoo… - The Journal of …, 2021 - ACS Publications
This report describes an efficient transition-metal-free process toward the transfer
hydrogenative cascade reaction between nitroarenes and amines or alcohols. The …

Gold‐Catalyzed One‐Pot Cycloisomerization/Nucleophilic Addition/Rearrangement of Acenaphthylene Carbaldehyde Derivatives

A Truchon, A Dupeux, S Olivero… - Advanced Synthesis & …, 2023 - Wiley Online Library
Merging the latest advances in the field of gold catalysis and the efficiency of hexafluoro‐2‐
propanol (HFIP), a gold‐catalyzed orthogonal tandem reaction has been developed to …

HFIP-mediated strategy towards β-oxo amides and subsequent Friedel-Craft type cyclization to 2‑quinolinones using recyclable catalyst

AK Kabi, R Gujjarappa, N Vodnala, D Kaldhi, U Tyagi… - Tetrahedron …, 2020 - Elsevier
A simple and cost-effective 1, 1, 1, 3, 3, 3-hexafluoro-2-propanol (HFIP)-mediated protocol
for the synthesis of β-oxo amides has been described by using amines and β-keto esters as …

Benzils: A review on their synthesis

SKJ Shaikh, RR Kamble… - Asian Journal of …, 2022 - Wiley Online Library
This review segregates and outlines all the aspects of the synthesis of Benzil for almost two
centuries. Here, state of the art review includes the early synthesis in 1836 to the …

A visible-light-induced photocatalyst-free approach for C-3 dicarbonyl coumarin production

J **, X Wu, M Huang, JK Kim, J Zhang, Y Li… - Chemical …, 2021 - pubs.rsc.org
A mild and efficient visible-light-induced synthesis of C-3 dicarbonyl coumarins from 3-
arylacetylene coumarins without a photocatalyst was reported. This iodide-mediated method …