Advances in microfluidic materials, functions, integration, and applications
PN Nge, CI Rogers, AT Woolley - Chemical reviews, 2013 - ACS Publications
Microfluidics consist of microfabricated structures for liquid handling, with cross sections in
the 1–500 μm range and small volume capacity (femtoliter to nanoliter). Capillary tubes …
the 1–500 μm range and small volume capacity (femtoliter to nanoliter). Capillary tubes …
Engineers are from PDMS-land, Biologists are from Polystyrenia
As the integration of microfluidics into cell biology research proceeds at an ever-increasing
pace, a critical question for those working at the interface of both disciplines is which device …
pace, a critical question for those working at the interface of both disciplines is which device …
3D printed microfluidic devices: a review focused on four fundamental manufacturing approaches and implications on the field of healthcare
In the last few years, 3D printing has emerged as a promising alternative for the fabrication
of microfluidic devices, overcoming some of the limitations associated with conventional soft …
of microfluidic devices, overcoming some of the limitations associated with conventional soft …
Fundamentals of microfluidic cell culture in controlled microenvironments
Microfluidics has the potential to revolutionize the way we approach cell biology research.
The dimensions of microfluidic channels are well suited to the physical scale of biological …
The dimensions of microfluidic channels are well suited to the physical scale of biological …
Advances in organ-on-a-chip materials and devices
The organ-on-a-chip (OoC) paves a way for biomedical applications ranging from preclinical
to clinical translational precision. The current trends in the in vitro modeling is to reduce the …
to clinical translational precision. The current trends in the in vitro modeling is to reduce the …
Tumour-on-a-chip: microfluidic models of tumour morphology, growth and microenvironment
Cancer remains one of the leading causes of death, albeit enormous efforts to cure the
disease. To overcome the major challenges in cancer therapy, we need to have a better …
disease. To overcome the major challenges in cancer therapy, we need to have a better …
Comparison of biocompatibility and adsorption properties of different plastics for advanced microfluidic cell and tissue culture models
PM van Midwoud, A Janse, MT Merema… - Analytical …, 2012 - ACS Publications
Microfluidic technology is providing new routes toward advanced cell and tissue culture
models to better understand human biology and disease. Many advanced devices have …
models to better understand human biology and disease. Many advanced devices have …
Oxygen control: the often overlooked but essential piece to create better in vitro systems
V Palacio-Castañeda, N Velthuijs, S Le Gac… - Lab on a Chip, 2022 - pubs.rsc.org
Variations in oxygen levels play key roles in numerous physiological and pathological
processes, but are often not properly controlled in in vitro models, introducing a significant …
processes, but are often not properly controlled in in vitro models, introducing a significant …
[HTML][HTML] The impact of microfluidics in high-throughput drug-screening applications
P De Stefano, E Bianchi, G Dubini - Biomicrofluidics, 2022 - pubs.aip.org
Drug discovery is an expensive and lengthy process. Among the different phases, drug
discovery and preclinical trials play an important role as only 5–10 of all drugs that begin …
discovery and preclinical trials play an important role as only 5–10 of all drugs that begin …
Microfluidic-based 3D engineered microvascular networks and their applications in vascularized microtumor models
X Wang, Q Sun, J Pei - Micromachines, 2018 - mdpi.com
The microvasculature plays a critical role in human physiology and is closely associated to
various human diseases. By combining advanced microfluidic-based techniques, the …
various human diseases. By combining advanced microfluidic-based techniques, the …