Objective The risk-benefit profile of antidepressant medications in bipolar disorder is
controversial. When conclusive evidence is lacking, expert consensus can guide treatment …

Objectives: Although clinically highly relevant, the recognition and treatment of bipolar mixed
states has played only an underpart in recent guidelines. This WFSBP guideline has been …

Objective: Little is known about how often bipolar depressive episodes are accompanied by
subsyndromal manic symptoms in bipolar I and II disorders. The authors sought to determine …

Objective Episodes of bipolar disorder are defined as depressive or manic, but depressive
and manic symptoms can combine in the same episode. Coexistence or rapid alternation of …

Objective: To estimate the frequency of mixed states in patients diagnosed with major
depressive episode (MDE) according to conceptually different definitions and to compare …

Objective To review the DSM‐5 proposed criteria for mixed depression in light of robust and
consistent historical and scientific evidence. Method An extensive historical search, a …

The DSM system has never acknowledged a central position for mixed states; thus, mixed
depressions have been almost completely neglected for decades. Now, DSM-5 is proposing …

Introduction Suicidal behavior is strongly associated with depression in major depressive
(MDD) and bipolar (BD) disorders, especially with associated behavioral activation …

Background The DSM-5 mixed features specifier for mood disorders encourages renewed
interest in mixed states and led us to pool research findings regarding prevalence of mixed …

Background Suicide is a leading cause of death for perinatal women. Identifying women at
risk of suicide is critical. Research on the validity and/or reliability of measures assessing …