Src is a non‐receptor cytoplasmic tyrosine kinase which becomes activated following the
stimulation of plasma membrane receptors including receptor tyrosine kinases and integrins …

Pancreatic ductal adenocarcinoma (PDAC) has one of the highest mortality rates among all
cancer types. Its delayed diagnosis precludes curative resection, thus most of the current …

Metastases remain the major cause of death from cancer. Recent molecular advances have
highlighted the importance of metabolic alterations in cancer cells, including the Warburg …

OBJECTIVES: To investigate immunohistochemical (IHC) analysis of E-cadherin, β-catenin,
APC and Vimentin for prediction of oral malignant transformation. MATERIALS AND …

The 20th century saw great advances in anatomy‐based (surgery and radiotherapy) and
chemotherapy approaches for treating head and neck squamous cell carcinoma (HNSCC) …

The mechanisms involved in the epithelial to mesenchymal transition (EMT) are integrated
in concert with master developmental and oncogenic pathways regulating in tumor growth …

Oral squamous cell carcinoma is a challenging oncology problem. A reliable biomarker for
metastasis or high-risk prognosis in oral cancer patients remains undefined. Using …

SRC is a tyrosine kinase that plays a role in oncogenic, invasive and bone-metastatic
processes. It has therefore been prioritized as a candidate therapeutic target in patients with …

Purpose: In carcinomas, invasive tumor growth is accompanied by desmoplastic stroma
reaction and facilitated by epithelial-mesenchymal transition (EMT) of cancer cells. We …

Focal adhesion kinase (FAK) and steroid receptor coactivator (Src) are intracellular
(nonreceptor) tyrosine kinases that physically and functionally interact to promote a variety of …