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[HTML][HTML] Antibacterial gas therapy: strategies, advances, and prospects
One of the challenges posed by current antibacterial therapy is that the expanded and
massive use of antibiotics endows bacteria with the ability to resist almost all kinds of …
massive use of antibiotics endows bacteria with the ability to resist almost all kinds of …
Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation
SW Ryter, AMK Choi - Translational Research, 2016 - Elsevier
The heme oxygenase-1 (HO-1) enzyme system remains an attractive therapeutic target for
the treatment of inflammatory conditions. HO-1, a cellular stress protein, serves a vital …
the treatment of inflammatory conditions. HO-1, a cellular stress protein, serves a vital …
[HTML][HTML] Ruthenium complexes in the fight against pathogenic microorganisms. An extensive review
The widespread use of antibiotics has resulted in the emergence of drug-resistant
populations of microorganisms. Clearly, one can see the need to develop new, more …
populations of microorganisms. Clearly, one can see the need to develop new, more …
[HTML][HTML] A thiol-reactive Ru (II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3
Carbon monoxide (CO)-releasing molecules (CORMs), mostly metal carbonyl compounds,
are extensively used as experimental tools to deliver CO, a biological 'gasotransmitter', in …
are extensively used as experimental tools to deliver CO, a biological 'gasotransmitter', in …
[HTML][HTML] 'Carbon-monoxide-releasing molecule-2 (CORM-2)'is a misnomer: ruthenium toxicity, not CO release, accounts for its antimicrobial effects
Carbon monoxide (CO)-releasing molecules (CORMs) are used to deliver CO, a biological
'gasotransmitter', in biological chemistry and biomedicine. CORMs kill bacteria in culture and …
'gasotransmitter', in biological chemistry and biomedicine. CORMs kill bacteria in culture and …
Heme oxygenase-1 as a modulator of intestinal inflammation development and progression
VP Sebastián, GA Salazar… - Frontiers in …, 2018 - frontiersin.org
Heme Oxygenase 1 (HMOX1) is an enzyme that catalyzes the reaction that degrades the
heme group contained in several important proteins, such as hemoglobin, myoglobin, and …
heme group contained in several important proteins, such as hemoglobin, myoglobin, and …
The microbiology of ruthenium complexes
Ruthenium is seldom mentioned in microbiology texts, due to the fact that this metal has no
known, essential roles in biological systems, nor is it generally considered toxic. Since the …
known, essential roles in biological systems, nor is it generally considered toxic. Since the …
Metal-based carbon monoxide releasing molecules with promising cytotoxic properties
Carbon monoxide, the “silent killer” gas, is increasingly recognised as an important
signalling molecule in human physiology, which has beneficial biological properties. A …
signalling molecule in human physiology, which has beneficial biological properties. A …
Ruthenium (II) carbon monoxide releasing molecules: Structural perspective, antimicrobial and anti-inflammatory properties
Carbon monoxide has recently emerged to promote tissue regeneration, enhance the innate
immune system, and have anti-inflammatory and antibacterial properties. While the first …
immune system, and have anti-inflammatory and antibacterial properties. While the first …
[HTML][HTML] Hydrogen sulfide and carbon monoxide tolerance in bacteria
Hydrogen sulfide and carbon monoxide share the ability to be beneficial or harmful
molecules depending on the concentrations to which organisms are exposed. Interestingly …
molecules depending on the concentrations to which organisms are exposed. Interestingly …