Develo**, Characterizing, and Modeling CRISPR-Based Point-of-Use Pathogen Diagnostics

JK Jung, KS Dreyer, KE Dray, JJ Muldoon… - ACS synthetic …, 2024 - ACS Publications
Recent years have seen intense interest in the development of point-of-care nucleic acid
diagnostic technologies to address the scaling limitations of laboratory-based approaches …

[HTML][HTML] RNA structure modulates Cas13 activity and enables mismatch detection

O Kimchi, BB Larsen, ORS Dunkley, AJW Te Velthuis… - bioRxiv, 2023 - ncbi.nlm.nih.gov
The RNA-targeting CRISPR nuclease Cas13 has emerged as a powerful tool for
applications ranging from nucleic acid detection to transcriptome engineering and RNA …

Towards AI-designed genomes using a variational autoencoder

NK Dudek, D Precup - Proceedings B, 2024 - royalsocietypublishing.org
Genomes encode elaborate networks of genes whose products must seamlessly interact to
support living organisms. Humans' capacity to understand these biological systems is limited …

Monitoring the Land and Sea: Enhancing Efficiency Through CRISPR-Cas Driven Depletion and Enrichment of Environmental DNA

A Kardailsky, B Durán-Vinet, G Nester… - The CRISPR …, 2025 - liebertpub.com
Characterizing biodiversity using environmental DNA (eDNA) represents a paradigm shift in
our capacity for biomonitoring complex environments, both aquatic and terrestrial. However …

Insights on Serology, CRISPR Diagnostics, and Machine Learning Architectures for Biological Sequences

SM Siddiqui - 2024 - dspace.mit.edu
Fueled by technological breakthroughs, advancements in our understanding of infectious
agents offer unprecedented potential for their early detection, intervention, and ultimately …

The CRISPR/Cas13 system edits viral spike and nucleocapsid RNA to resist SARS-CoV-2 infection

L Wang, WJ Wang, RX Luo, ZL Ke, WY Tian - 2023 - researchsquare.com
Background As a new type of virus that seriously threatens public health worldwide, there
are currently very limited effective methods of prevention and control for severe acute …