A cell's decision to die is controlled by a sophisticated network whose deregulation
contributes to the pathogenesis of multiple diseases including neoplastic and …

Mitochondria contain two aqueous compartments: the matrix and the intermembrane space.
Whereas many of the biologic functions of the matrix were well characterized in the past, it …

Background Eukaryotic cells have evolved various response mechanisms to counteract the
deleterious consequences of oxidative stress. Among these processes, metabolic alterations …

Reactive oxygen species (ROS), play important roles in cellular signaling, nonetheless are
toxic at higher concentrations. Cells have many interconnected, overlapped or backup …

Mitochondrial involvement in yeast apoptosis is probably the most unifying feature in the
field. Reports proposing a role for mitochondria in yeast apoptosis present evidence ranging …

Plant defensins are active against plant and human pathogenic fungi (such as Candida
albicans) and baker's yeast. However, they are non-toxic to human cells, providing a …

Nitric oxide (NO) is a small molecule with distinct roles in diverse physiological functions in
biological systems, among them the control of the apoptotic signalling cascade. By …

The effect of high temperature and oxidative stress on the cell viability of the yeast
antagonist, Metschnikowia fructicola was determined. A mild heat shock (HS) pretreatment …

Although acetic acid has been shown to induce apoptosis in yeast, the exact apoptotic
mechanisms remain unknown. Here, we studied the effects of acetic acid treatment on yeast …

The study of cell death mechanisms in fungi, particularly yeasts, has gained substantial
interest in recent decades driven by the potential for biotechnological advancements and …