The therapeutic potential of naringenin: a review of clinical trials

B Salehi, PVT Fokou, M Sharifi-Rad, P Zucca… - Pharmaceuticals, 2019 - mdpi.com
Naringenin is a flavonoid belonging to flavanones subclass. It is widely distributed in several
Citrus fruits, bergamot, tomatoes and other fruits, being also found in its glycosides form …

Therapeutic potential of flavonoids in pain and inflammation: mechanisms of action, pre-clinical and clinical data, and pharmaceutical development

CR Ferraz, TT Carvalho, MF Manchope, NA Artero… - Molecules, 2020 - mdpi.com
Pathological pain can be initiated after inflammation and/or peripheral nerve injury. It is a
consequence of the pathological functioning of the nervous system rather than only a …

Naringenin nano-delivery systems and their therapeutic applications

M Bhia, M Motallebi, B Abadi, A Zarepour… - Pharmaceutics, 2021 - mdpi.com
Naringenin (NRG) is a polyphenolic phytochemical belonging to the class of flavanones and
is widely distributed in citrus fruits and some other fruits such as bergamot, tomatoes, cocoa …

An electrospun scaffold functionalized with a ROS-scavenging hydrogel stimulates ocular wound healing

X Shi, T Zhou, S Huang, Y Yao, P Xu, S Hu, C Tu… - Acta Biomaterialia, 2023 - Elsevier
Abstracts Ocular alkali burn is a serious ophthalmic emergency. Highly penetrative alkalis
cause strong inflammatory responses leading to persistent epithelial defects, acute corneal …

Naringenin prolongs lifespan and delays aging mediated by IIS and MAPK in Caenorhabditis elegans

Y Ge, H Chen, J Wang, G Liu, SW Cui, J Kang… - Food & Function, 2021 - pubs.rsc.org
Naringenin (NN) is one of the most abundant flavonoids in citrus and grapefruits and has
been shown to have antioxidant properties in vitro. The purpose of the study is to examine …

Naringenin as a possible candidate against SARS-CoV-2 infection and in the pathogenesis of COVID-19

PK Agrawal, C Agrawal… - Natural Product …, 2021 - journals.sagepub.com
Naringenin, widely distributed in fruits and vegetables, is endowed with antiviral and other
health beneficial activities, such as immune-stimulating and anti-inflammatory actions that …

Pathogenesis of alkali injury-induced limbal stem cell deficiency: a literature survey of animal models

L Sprogyte, M Park, N Di Girolamo - Cells, 2023 - mdpi.com
Limbal stem cell deficiency (LSCD) is a debilitating ocular surface disease that eventuates
from a depleted or dysfunctional limbal epithelial stem cell (LESC) pool, resulting in corneal …

[HTML][HTML] The potential benefits of polyphenols for corneal diseases

J Feng, Y Zhang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The cornea functions as the primary barrier of the ocular surface, regulating temperature and
humidity while providing protection against oxidative stress, harmful stimuli and pathogenic …

Reactive Oxygen Species─ Responsive Lipid Nanoparticles for Effective RNAi and Corneal Neovascularization Therapy

A Liu, C Liang, J Liu, Y Huang, M Wang… - Acs Applied Materials & …, 2022 - ACS Publications
Corneal neovascularization (CNV) is a common disease that affects the vision ability of more
than 1 million people annually. Small interfering RNA (siRNA) delivery nanoparticle …

Potential therapeutic effects of polyphenols in Parkinson's disease: in vivo: and: in vitro: pre-clinical studies

C Giuliano, S Cerri, F Blandini - Neural Regeneration Research, 2021 - journals.lww.com
Parkinson's disease is a neurodegenerative disorder characterized by a combination of
severe motor and non-motor symptoms. Over the years, several factors have been …