Mortality in sepsis and septic shock in Europe, North America and Australia between 2009 and 2019—results from a systematic review and meta-analysis
M Bauer, H Gerlach, T Vogelmann, F Preissing… - Critical Care, 2020 - Springer
Background Sepsis and septic shock remain drivers for mortality in critically ill patients. The
heterogeneity of the syndrome hinders the generation of reproducible numbers on mortality …
heterogeneity of the syndrome hinders the generation of reproducible numbers on mortality …
The neutrophil's role during health and disease
Neutrophils have always been considered as uncomplicated front-line troopers of the innate
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …
Ignore, trust, or negotiate: understanding clinician acceptance of AI-based treatment recommendations in health care
Artificial intelligence (AI) in healthcare has the potential to improve patient outcomes, but
clinician acceptance remains a critical barrier. We developed a novel decision support …
clinician acceptance remains a critical barrier. We developed a novel decision support …
Sepsis: The evolution in definition, pathophysiology, and management
B Gyawali, K Ramakrishna… - SAGE open …, 2019 - journals.sagepub.com
There has been a significant evolution in the definition and management of sepsis over the
last three decades. This is driven in part due to the advances made in our understanding of …
last three decades. This is driven in part due to the advances made in our understanding of …
The third international consensus definitions for sepsis and septic shock (Sepsis-3)
Importance Definitions of sepsis and septic shock were last revised in 2001. Considerable
advances have since been made into the pathobiology (changes in organ function …
advances have since been made into the pathobiology (changes in organ function …
Develo** a new definition and assessing new clinical criteria for septic shock: for the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis …
Importance Septic shock currently refers to a state of acute circulatory failure associated with
infection. Emerging biological insights and reported variation in epidemiology challenge the …
infection. Emerging biological insights and reported variation in epidemiology challenge the …
Assessment of global incidence and mortality of hospital-treated sepsis. Current estimates and limitations
C Fleischmann, A Scherag, NKJ Adhikari… - American journal of …, 2016 - atsjournals.org
Rationale: Reducing the global burden of sepsis, a recognized global health challenge,
requires comprehensive data on the incidence and mortality on a global scale. Objectives …
requires comprehensive data on the incidence and mortality on a global scale. Objectives …
[PDF][PDF] Goal-directed resuscitation for patients with early septic shock
Background Early goal-directed therapy (EGDT) has been endorsed in the guidelines of the
Surviving Sepsis Campaign as a key strategy to decrease mortality among patients …
Surviving Sepsis Campaign as a key strategy to decrease mortality among patients …
The epidemiology of sepsis in Brazilian intensive care units (the Sepsis PREvalence Assessment Database, SPREAD): an observational study
Background The sepsis burden on acute care services in middle-income countries is a
cause for concern. We estimated incidence, prevalence, and mortality of sepsis in adult …
cause for concern. We estimated incidence, prevalence, and mortality of sepsis in adult …
Mortality related to severe sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000-2012
Importance Severe sepsis and septic shock are major causes of mortality in intensive care
unit (ICU) patients. It is unknown whether progress has been made in decreasing their …
unit (ICU) patients. It is unknown whether progress has been made in decreasing their …