Diabetic nephropathy: update on pillars of therapy slowing progression

SC Naaman, GL Bakris - Diabetes Care, 2023 - Am Diabetes Assoc
Management of diabetic kidney disease (DKD) has evolved in parallel with our growing
understanding of the multiple interrelated pathophysiological mechanisms that involve …

Update on diabetic kidney disease (DKD): focus on non-albuminuric DKD and cardiovascular risk

S Scilletta, M Di Marco, N Miano, A Filippello… - Biomolecules, 2023 - mdpi.com
The classic description of diabetic kidney disease (DKD) involves progressive stages of
glomerular hyperfiltration, microalbuminuria, proteinuria, and a decline in the estimated …

High-density lipoprotein subclasses and cardiovascular disease and mortality in type 2 diabetes: analysis from the Hong Kong Diabetes Biobank

Q **, ESH Lau, AO Luk, CHT Tam, R Ozaki… - Cardiovascular …, 2022 - Springer
Objective High-density lipoproteins (HDL) comprise particles of different size, density and
composition and their vasoprotective functions may differ. Diabetes modifies the composition …

SGLT2 inhibitors reduce adverse kidney and cardiovascular events in patients with advanced diabetic kidney disease: A population-based propensity score-matched …

GCK Chan, JKC Ng, KM Chow, CC Szeto - Diabetes research and clinical …, 2023 - Elsevier
Background There were limited data on the efficacy and safety profile on use of sodium–
glucose co-transporter 2 receptor (SGLT2) inhibitors in diabetic patients with advanced …

A review of the latest real‐world evidence studies in diabetic kidney disease: What have we learned about clinical practice and the clinical effectiveness of …

F Bonnet, ME Cooper, L Koppe… - Diabetes, Obesity …, 2024 - Wiley Online Library
Diabetic nephropathy, also known as diabetic kidney disease (DKD), remains a challenge in
clinical practice as this is the major cause of kidney failure worldwide. Clinical trials do not …

Combination therapy for kidney disease in people with diabetes mellitus

DH van Raalte, P Bjornstad, DZI Cherney… - Nature Reviews …, 2024 - nature.com
Diabetic kidney disease (DKD), defined as co-existing diabetes and chronic kidney disease
in the absence of other clear causes of kidney injury, occurs in approximately 20–40% of …

Circulating metabolomic markers linking diabetic kidney disease and incident cardiovascular disease in type 2 diabetes: analyses from the Hong Kong Diabetes …

Q **, ESH Lau, AO Luk, CHT Tam, R Ozaki, CKP Lim… - Diabetologia, 2024 - Springer
Aims/hypothesis The aim of this study was to describe the metabolome in diabetic kidney
disease (DKD) and its association with incident CVD in type 2 diabetes, and identify …

[HTML][HTML] Precision medicine approaches to diabetic kidney disease: Personalized interventions on the horizon

FNU Nageeta, F Waqar, I Allahi, F Murtaza, M Nasir… - Cureus, 2023 - ncbi.nlm.nih.gov
Diabetic kidney disease (DKD) is a significant complication of diabetes that requires
innovative interventions to address its increasing impact. Precision medicine is a rapidly …

Prevalence of Diabetic Kidney Disease with Different Subtypes in Hospitalized Patients with Diabetes and Correlation Between eGFR and LncRNA XIST Expression …

Y Lin, P Wu, L Guo, Q Feng, L Wang, X Lin, C Yang… - Diabetes Therapy, 2023 - Springer
Introduction Diabetic kidney disease (DKD) has become the leading cause of end-stage
kidney disease (ESKD) in most countries. Recently, long noncoding RNA XIST has been …

Association of eGFR slope with all-cause mortality, macrovascular and microvascular outcomes in people with type 2 diabetes and early-stage chronic kidney disease

Q **, CLK Lam, EYF Wan - Diabetes Research and Clinical Practice, 2023 - Elsevier
Aims The association of estimated glomerular filtration rate (eGFR) slope with progression of
complications in people with type 2 diabetes (T2D) and early-stage chronic kidney disease …