Abstract Streptozotocin (STZ), a glucosamine-nitrosourea compound derived from soil
bacteria and originally developed as an anticancer agent, in 1963 has been found to induce …

Alzheimer's disease (AD) can be divided into sporadic AD (SAD) and familial AD (FAD).
Most AD cases are sporadic and result from multiple etiologic factors, including …

Experimental models that faithfully mimic the developmental pathology of sporadic
Alzheimer's disease (sAD) in humans are important for testing the novel therapeutic …

Alzheimer's disease (AD) is a degenerative disease of the nervous system. Glucagon-like
peptide-1 receptor agonists (GLP-1 RAs), a drug used to treat type 2 diabetes, have been …

Alzheimer's Disease is a degenerative neurological condition which leads to a decline in
memory and cognitive function. Chlorogenic Acid (CGA) presents properties including …

Alzheimer's disease (AD) is a neurodegenerative disorder that is remarkably characterized
by pathological hallmarks which include amyloid plaques, neurofibrillary tangles, neuronal …

Intracerebroventricular (icv) streptozotocin (STZ) administration induces pathological and
behavioral alterations similar to those observed in Alzheimer's disease (AD) and is thus …

Alzheimer's disease (AD) is prevalent in old age people and is one of the most common
brain diseases. Brain insulin resistance, neuroinflammation, oxidative stress, and …

Anthocyanins (ANT) are polyphenolic flavonoids with antioxidant and neuroprotective
properties. This study evaluated the effect of ANT treatment on cognitive performance and …

The long term effect of single (day 1) and twice (day 1 and 3) injections of
intracerebroventricular (ICV) streptozotocin (STZ) at the doses of 1 and 3 mg/kg on the …