Recent advances in the natural products-based lead discovery for new agrochemicals

P Zhang, CB Duan, B **, AS Ali, X Han, H Zhang… - Advanced …, 2023 - Elsevier
Crops will be harmed by fungi, pests and weeds during their growth. In the past half century,
scientists have conducted in-depth research on natural products extracted from …

Do novel insecticides pose a threat to beneficial insects?

H Siviter, F Muth - Proceedings of the Royal Society B, 2020 - royalsocietypublishing.org
Systemic insecticides, such as neonicotinoids, are a major contributor towards beneficial
insect declines. This has led to bans and restrictions on neonicotinoid use globally, most …

Lethal and sublethal synergistic effects of a new systemic pesticide, flupyradifurone (Sivanto®), on honeybees

S Tosi, JC Nieh - Proceedings of the Royal Society B, 2019 - royalsocietypublishing.org
The honeybee (Apis mellifera L.) is an important pollinator and a model for pesticide effects
on insect pollinators. The effects of agricultural pesticides on honeybee health have …

Latest generation of halogen‐containing pesticides

P Jeschke - Pest management science, 2017 - Wiley Online Library
Agriculture is confronted with enormous challenges, from production of enough high‐quality
food to water use, environmental impacts and issues combined with a continually growing …

Field‐realistic neonicotinoid exposure has sub‐lethal effects on non‐Apis bees: A meta‐analysis

H Siviter, SK Richman, F Muth - Ecology Letters, 2021 - Wiley Online Library
Neonicotinoid insecticides can have sub‐lethal effects on bees which has led to calls from
conservationists for a global ban. In contrast, agrochemical companies argue that …

Long-term field-realistic exposure to a next-generation pesticide, flupyradifurone, impairs honey bee behaviour and survival

S Tosi, JC Nieh, A Brandt, M Colli, J Fourrier… - Communications …, 2021 - nature.com
The assessment of pesticide risks to insect pollinators have typically focused on short-term,
lethal impacts. The environmental ramifications of many of the world's most commonly …

Combined nutritional stress and a new systemic pesticide (flupyradifurone, Sivanto®) reduce bee survival, food consumption, flight success, and thermoregulation

L Tong, JC Nieh, S Tosi - Chemosphere, 2019 - Elsevier
Abstract Flupyradifurone (FPF, Sivanto®) is a new butenolide insecticide that, like the
neonicotinoids, is a systemic nicotinic acetylcholine receptor (nAChR) agonist. However …

Effects of the novel pesticide flupyradifurone (Sivanto) on honeybee taste and cognition

H Hesselbach, R Scheiner - Scientific reports, 2018 - nature.com
Due to intensive agriculture honeybees are threatened by various pesticides. The use of one
group of them, the neonicotinoids, was recently restricted by the European Union. These …

Field‐realistic exposure to the novel insecticide flupyradifurone reduces reproductive output in a bumblebee (Bombus impatiens)

LI Richardson, H Siviter, S Jha… - Journal of Applied …, 2024 - Wiley Online Library
Novel insecticides are continuously being developed for application in response to
increased legal restriction of previously developed insecticides and resistance in target …

[HTML][HTML] A toxicogenomics approach reveals characteristics supporting the honey bee (Apis mellifera L.) safety profile of the butenolide insecticide flupyradifurone

J Haas, M Zaworra, J Glaubitz, G Hertlein… - Ecotoxicology and …, 2021 - Elsevier
Flupyradifurone, a novel butenolide insecticide, selectively targets insect nicotinic
acetylcholine receptors (nAChRs), comparable to structurally different insecticidal …