Dysarthria in Parkinson's disease can be characterised by monotony of pitch and loudness,
reduced stress, variable rate, imprecise consonants, and a breathy and harsh voice. Use of …

Converging insights into attention-deficit/hyperactivity disorder (ADHD) support the notion
that ADHD is best characterized behaviorally as a disorder of self-regulation or executive …

INTRODUCTION.: The long-lasting beneficial effects of subthalamic nucleus (STN) deep
brain stimulation (DBS) on motor function have now largely been acknowledged. Whereas …

The effects of posterior internal pallidal ablation (GPi pallidotomy) on parkinsonian signs
and symptoms were studied in 15 patients with medically intracally intractable Parkinson's …

Background Posteroventral medial pallidotomy sometimes produces striking improvement in
patients with advanced Parkinson's disease, but the studies to date have involved small …

Object. The authors describe the microelectrode recording and stimulation techniques used
for localizing the caudal sensorimotor portion of the globus pallidus internus (GPi) and …

Thirty‐six patients with Parkinson's disease (PD) were randomized to either medical therapy
(N= 18) or unilateral GPi pallidotomy (N= 18). The primary outcome variable was the change …

Object. Stereotactic brain biopsy has played an integral role in the diagnosis and
management of brain lesions. At most centers, imaging studies following biopsy are rarely …

We studied the effects—on parkinsonian signs, on levodopa‐induced dyskinesias, and on
levodopa response—of acute experimental high‐frequency stimulation of the internal …

OBJECTIVE: The subthalamic nucleus (STN) has recently become the surgical target of
choice for the treatment of medically refractory idiopathic Parkinson's disease. A number of …