The reconstruction of musculoskeletal defects is a constant challenge for orthopaedic
surgeons. Musculoskeletal injuries such as fractures, chondral lesions, infections and tumor …

Critical‐sized defects in bone, whether induced by primary tumor resection, trauma, or
selective surgery have in many cases presented insurmountable challenges to the current …

Here, we fabricated thermosensitive injectable hydrogel containing poly (N-
isopropylacrylamide)(PNIPAAm)-based copolymer/graphene oxide (GO) composite with …

Abstract 3D printing technique is the most sophisticated technique to produce scaffolds with
tailorable physical properties. But, these scaffolds often suffer from limited biological …

As life expectancy increases, malfunction or loss of tissue caused by injury or disease leads
to reduced quality of life in many patients at significant socioeconomic cost. Even though …

Critical sized bone defects have to be filled with material to allow bone healing. The golden
standard for this treatment is autogenous bone grafting. Because of donor size morbidity …

Importance of the field: Biomimetic scaffolds and substrates of extracellular matrices (ECMs)
play an important role in the regulation of cell function and in the guidance of new tissue …

The development and application of decellularized extracellular matrices (ECM) has grown
rapidly in the fields of cell biology, tissue engineering and regenerative medicine in recent …

Zeolitic imidazolate framework-8 (ZIF-8) is an important type of metal organic framework and
has found numerous applications in the biomedical field. Our previous studies have …

Tissue engineering (TE)-based bone grafts are favorable alternatives to autografts and
allografts. Both biochemical properties and the architectural features of TE scaffolds are …