A considerable and unanticipated plasticity of the human genome, manifested as inter-
individual copy number variation, has been discovered. These structural changes constitute …

Childhood tumors containing cells that are morphologically and functionally similar to
normal progenitor cells provide fertile ground for investigating the links between …

Loss of heterozygosity (LOH) and copy number alteration (CNA) feature prominently in the
somatic genomic landscape of tumors. As such, karyotypic aberrations in cancer genomes …

We describe a method for automatic detection of absolute segmental copy numbers and
genotype status in complex cancer genome profiles measured with single-nucleotide …

This review gives an account of chromosomal aberrations in cancer cells. Such
abnormalities have typically been associated with hematologic cancers, but recent work has …

Epithelial cancers inflict a heavy human and social burden. It was estimated [Tyczynski JE,
Bray F, Parkin DM. Lung cancer in Europe in 2000: epidemiology, prevention, and early …

Bladder cancer (BC) has been associated with genetic susceptibility. Single peptide
polymorphisms (SNPs) can modulate BC susceptibility. A literature search was performed …

Purpose: Follicular lymphoma (FL) constitutes the second most common non-Hodgkin's
lymphoma in the Western world. The clinical course is variable and only in part explained by …

Advances in understanding the molecular underpinnings of cancer and in molecular
diagnostic technologies have changed the clinical practice of oncologic pathology. The …

Monosomy 7 and interstitial deletions in the long arm of chromosome 7 (− 7/7q−) is a
common nonrandom chromosomal abnormality found frequently in myeloid disorders …