The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and
hyperactivation, highlights the potential of immune renormalization as a promising strategy …

As a nontraditional T-cell subgroup, γδT cells have gained popularity in the field of
immunotherapy in recent years. They have extraordinary antitumor potential and prospects …

Molecular profiles of tumors and tumor-associated cells hold great promise as biomarkers of
clinical outcomes. However, existing data sets are fragmented and difficult to analyze …

Burn are diverse and complex injuries that not only have local effects but also serious
systemic consequences through severe and prolonged inflammatory response. They are …

Allergic asthma is a complex and chronic inflammatory disorder which is associated with
airway hyper-responsiveness and tissue remodelling of the airway structure. Although …

We describe here a new subset of T cells, found in humans, mice, and cattle. These cells
bear a canonical T cell receptor (TCR) α chain containing hAV7S2 and AJ33 in humans and …

The tripartite subdivision of lymphocytes into B cells, αβ T cells, and γδ cells has been
conserved seemingly since the emergence of jawed vertebrates, more than 450 million …

The immune system develops in waves during ontogeny; it is initially populated by cells
generated from fetal hematopoietic stem cells (HSCs) and later by cells derived from adult …

Bisphosphonates are well-known inhibitors of osteoclastic bone resorption, but recent
clinical reports support the possibility of direct or indirect antitumor effects by these …

Most human peripheral blood γδ T lymphocytes respond to hitherto unidentified
mycobacterial antigens. Four ligands from Mycobacterium tuberculosis strain H37Rv that …