Abstract Since the Great Oxidation Event, about 2.4 billion years ago, the Earth is immersed
in an oxidizing atmosphere. Thus, it has been proposed that excess oxygen, originally a …

ROS include hydroxyl radicals (HO.), superoxide (O2..), and hydrogen peroxide (H2O2).
ROS are typically produced under physiological conditions and play crucial roles in living …

Mitochondrial dynamics are balanced fission and fusion events that regulate mitochondrial
morphology, and alteration in these events results in mitochondrial dysfunction and …

Diabetic nephropathy is a common complication of type I and type II diabetes, in which renal
glomeruli are destroyed, resulting in renal damage, proteinuria, and hypertension …

Macroautophagy/autophagy is an evolutionally conserved catabolic process in which
cytosolic contents, such as aggregated proteins, dysfunctional organelle, or invading …

Autophagy, a self-degradative process vital for cellular homeostasis, plays a significant role
in adipose tissue metabolism and tumorigenesis. This review aims to elucidate the complex …

Our study explored the tumor-suppressive effect of curcumin on cervical cancer cells.
Cervical cancer is one of the most common cancers among women worldwide. Acquired …

Autophagy and the lysosomal system, together referred to as the autophagolysosomal
system, is a cellular quality control network which maintains cellular health and homeostasis …

Redox homeostasis refers to the dynamic equilibrium between oxidant and reducing agent
in the body which plays a crucial role in maintaining normal physiological activities of the …

Increasing evidence suggests a strong interplay between autophagy and genomic stability.
Recently, several papers have demonstrated a molecular connection between the DNA …