Mesenchymal stem cells as trophic mediators
AI Caplan, JE Dennis - Journal of cellular biochemistry, 2006 - Wiley Online Library
Abstract Adult marrow‐derived Mesenchymal Stem Cells (MSCs) are capable of dividing
and their progeny are further capable of differentiating into one of several mesenchymal …
and their progeny are further capable of differentiating into one of several mesenchymal …
[HTML][HTML] Ischemia/reperfusion
T Kalogeris, CP Baines, M Krenz… - Comprehensive …, 2016 - ncbi.nlm.nih.gov
Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …
are the most common causes of debilitating disease and death in westernized cultures. The …
Exosome-shuttled miR-216a-5p from hypoxic preconditioned mesenchymal stem cells repair traumatic spinal cord injury by shifting microglial M1/M2 polarization
W Liu, Y Rong, J Wang, Z Zhou, X Ge, C Ji… - Journal of …, 2020 - Springer
Background Spinal cord injury (SCI) can lead to severe motor and sensory dysfunction with
high disability and mortality. In recent years, mesenchymal stem cell (MSC)-secreted nano …
high disability and mortality. In recent years, mesenchymal stem cell (MSC)-secreted nano …
An acute immune response underlies the benefit of cardiac stem cell therapy
Clinical trials using adult stem cells to regenerate damaged heart tissue continue to this
day,, despite ongoing questions of efficacy and a lack of mechanistic understanding of the …
day,, despite ongoing questions of efficacy and a lack of mechanistic understanding of the …
Paracrine mechanisms in adult stem cell signaling and therapy
Animal and preliminary human studies of adult cell therapy following acute myocardial
infarction have shown an overall improvement of cardiac function. Myocardial and vascular …
infarction have shown an overall improvement of cardiac function. Myocardial and vascular …
Heart regeneration
MA Laflamme, CE Murry - Nature, 2011 - nature.com
Heart failure plagues industrialized nations, killing more people than any other disease. It
usually results from a deficiency of specialized cardiac muscle cells known as …
usually results from a deficiency of specialized cardiac muscle cells known as …
Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial
Background Emerging evidence suggests that stem cells and progenitor cells derived from
bone marrow can be used to improve cardiac function in patients after acute myocardial …
bone marrow can be used to improve cardiac function in patients after acute myocardial …
Hypoxic mesenchymal stem cell-derived exosomes promote bone fracture healing by the transfer of miR-126
W Liu, L Li, Y Rong, D Qian, J Chen, Z Zhou, Y Luo… - Acta biomaterialia, 2020 - Elsevier
Increasing evidence has suggested that paracrine mechanisms might be involved in the
underlying mechanism of mesenchymal stem cells (MSCs) transplantation, and exosomes …
underlying mechanism of mesenchymal stem cells (MSCs) transplantation, and exosomes …
Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy
The most common form of heart failure occurs with normal systolic function and often
involves cardiac hypertrophy in the elderly. To clarify the biological mechanisms that drive …
involves cardiac hypertrophy in the elderly. To clarify the biological mechanisms that drive …
Cardiomyocyte regeneration: a consensus statement
Circulation. 2017; 136: 680–686. DOI: 10.1161/CIRCULATIONAHA. 117.029343 August 15,
2017 681 proliferation. 5 It remains unclear whether this regenerative window exists in large …
2017 681 proliferation. 5 It remains unclear whether this regenerative window exists in large …