In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …

This is the first comprehensive review on methods and materials for use in optical sensing of
pH values and on applications of such sensors. The Review starts with an introduction that …

Hydrogels are excellent water-swollen polymeric materials for use in wearable, implantable,
and disposable biosensors. Hydrogels have unique properties such as low cost, ease of …

Organic luminescent materials have attracted significant attention in the past few years due
to their fascinating photophysical properties. Implementing these emissive organic …

Micro-/nanorobots (MNRs) can be autonomously propelled on demand in complex
biological environments and thus may bring revolutionary changes to biomedicines …

Hybrid small-molecule/protein fluorescent probes are powerful tools for visualizing protein
localization and function in living cells. These hybrid probes are constructed by diverse site …

Bayesian optimization (BayesOpt) is a gold standard for query-efficient continuous
optimization. However, its adoption for drug design has been hindered by the discrete, high …

We report the engineering of mScarlet, a truly monomeric red fluorescent protein with record
brightness, quantum yield (70%) and fluorescence lifetime (3.9 ns). We developed mScarlet …

Many researchers, especially those new to the field, need to determine which criteria are
essential for demonstrating autophagy, either for the purposes of their own research, or in …

Acting as a bridge between the cytoskeleton of the cell and the extra cellular matrix (ECM),
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …