Biomedical engineering strategies for peripheral nerve repair: surgical applications, state of the art, and future challenges

BJ Pfister, T Gordon, JR Loverde… - Critical Reviews™ in …, 2011 - dl.begellhouse.com
Damage to the peripheral nervous system is surprisingly common and occurs primarily from
trauma or a complication of surgery. Although recovery of nerve function occurs in many mild …

Cell therapy for spinal cord regeneration

SM Willerth, SE Sakiyama-Elbert - Advanced drug delivery reviews, 2008 - Elsevier
This review presents a summary of the various types of cellular therapy used to treat spinal
cord injury. The inhibitory environment and loss of axonal connections after spinal cord …

Acellular nerve allografts in major peripheral nerve repairs: an analysis of cases presenting with limited recovery

BR Peters, MD Wood, DA Hunter, SE Mackinnon - Hand, 2023 - journals.sagepub.com
Background: Acellular nerve allografts have been used successfully and with increasing
frequency to reconstruct nerve injuries. As their use has been expanded to treat longer gap …

End-to-side neurorrhaphy using an electrospun PCL/collagen nerve conduit for complex peripheral motor nerve regeneration

BK Lee, YM Ju, JG Cho, JD Jackson, SJ Lee, A Atala… - Biomaterials, 2012 - Elsevier
In cases of complex neuromuscular defects, finding the proximal stump of a transected nerve
in order to restore innervation to damaged muscle is often impossible. In this study we …

Recent therapeutic strategies for spinal cord injury treatment: possible role of stem cells

D Garbossa, M Boido, M Fontanella, C Fronda… - Neurosurgical …, 2012 - Springer
Spinal cord injury (SCI) often results in significant dysfunction and disability. A series of
treatments have been proposed to prevent and overcome the formation of the glial scar and …

Alternatives to sural nerve grafts in the upper extremity

LH Poppler, K Davidge, JCY Lu, J Armstrong, IK Fox… - Hand, 2015 - journals.sagepub.com
Background The sural nerve is the most common nerve graft donor despite requiring a
second operative limb and causing numbness of the lateral foot. The purposes of this study …

The medial antebrachial cutaneous nerve is a low-morbidity alternative to the standard sural nerve autograft

S Pripotnev, SL Pinni, S Zhou, G Skolnick… - Hand, 2024 - journals.sagepub.com
Background: Nerve interposition grafting is an important technique in nerve reconstructive
surgery that is used when a primary repair is not feasible without significant tension. This …

Age‐related differences in the reinnervation after peripheral nerve injury

U Kovačič, J Sketelj, FF Bajrović - International review of neurobiology, 2009 - Elsevier
Numerous and extensive functional, structural, and biochemical changes characterize intact
aged peripheral nervous system. Functional recovery after peripheral nerve injury depends …

Updates in targeted sensory reinnervation for upper limb amputation

JS Hebert, K Elzinga, KM Chan, J Olson… - Current Surgery …, 2014 - Springer
Advanced robotic devices capable of simulating the dexterous ability of the upper limb with
an array of internal sensors have raised the enticing prospect of replacing the lost intricate …

Recent advances and developments in neural repair and regeneration for hand surgery

M Chimutengwende-Gordon… - The open orthopaedics …, 2012 - pmc.ncbi.nlm.nih.gov
End-to-end suture of nerves and autologous nerve grafts are the 'gold standard'for repair
and reconstruction of peripheral nerves. However, techniques such as sutureless nerve …