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Pulmonary drug delivery: from generating aerosols to overcoming biological barriers—therapeutic possibilities and technological challenges
CA Ruge, J Kirch, CM Lehr - The lancet Respiratory medicine, 2013 - thelancet.com
Research in pulmonary drug delivery has focused mainly on new particle or device
technologies to improve the aerosol generation and pulmonary deposition of inhaled drugs …
technologies to improve the aerosol generation and pulmonary deposition of inhaled drugs …
Microscale imaging of cilia-driven fluid flow
BK Huang, MA Choma - Cellular and molecular life sciences, 2015 - Springer
Cilia-driven fluid flow is important for multiple processes in the body, including respiratory
mucus clearance, gamete transport in the oviduct, right–left patterning in the embryonic …
mucus clearance, gamete transport in the oviduct, right–left patterning in the embryonic …
Entrainment of mammalian motile cilia in the brain with hydrodynamic forces
N Pellicciotta, E Hamilton, J Kotar, M Faucourt… - Proceedings of the …, 2020 - pnas.org
Motile cilia are widespread across the animal and plant kingdoms, displaying complex
collective dynamics central to their physiology. Their coordination mechanism is not …
collective dynamics central to their physiology. Their coordination mechanism is not …
ciliaFA: a research tool for automated, high-throughput measurement of ciliary beat frequency using freely available software
Background Analysis of ciliary function for assessment of patients suspected of primary
ciliary dyskinesia (PCD) and for research studies of respiratory and ependymal cilia requires …
ciliary dyskinesia (PCD) and for research studies of respiratory and ependymal cilia requires …
Assessing the collective dynamics of motile cilia in cultures of human airway cells by multiscale DDM
L Feriani, M Juenet, CJ Fowler, N Bruot, M Chioccioli… - Biophysical journal, 2017 - cell.com
The technique of differential dynamic microscopy is extended here, showing that it can
provide a powerful and objective method of video analysis for optical microscopy videos of …
provide a powerful and objective method of video analysis for optical microscopy videos of …
A novel exposure system for the efficient and controlled deposition of aerosol particles onto cell cultures
M Savi, M Kalberer, D Lang, M Ryser… - Environmental …, 2008 - ACS Publications
Epidemiologic studies have shown correlations between morbidity and particles≤ 2.5 μm
generated from pollution processes and manufactured nanoparticles. Thereby nanoparticles …
generated from pollution processes and manufactured nanoparticles. Thereby nanoparticles …
In vivo volumetric depth-resolved imaging of cilia metachronal waves using dynamic optical coherence tomography
T ** ciliary dynamics and coordination in response to CFTR-modulators in Cystic Fibrosis respiratory epithelial cells
M Chioccioli, L Feriani, J Kotar, PE Bratcher… - Nature …, 2019 - nature.com
Personalized approaches for systematically assessing ciliary beat dynamics and for drug
testing would improve the challenging task of diagnosing and treating respiratory disorders …
testing would improve the challenging task of diagnosing and treating respiratory disorders …