Unconventional T cells in brain homeostasis, injury and neurodegeneration
M Lv, Z Zhang, Y Cui - Frontiers in Immunology, 2023 - frontiersin.org
The interaction between peripheral immune cells and the brain is an important component of
the neuroimmune axis. Unconventional T cells, which include natural killer T (NKT) cells …
the neuroimmune axis. Unconventional T cells, which include natural killer T (NKT) cells …
Lipid hijacking: a unifying theme in vector-borne diseases
Vector-borne illnesses comprise a significant portion of human maladies, representing 17%
of global infections. Transmission of vector-borne pathogens to mammals primarily occurs …
of global infections. Transmission of vector-borne pathogens to mammals primarily occurs …
Cytokine networks as targets for preventing and controlling Chagas heart disease
CC Koh, EGA Neves, TG de Souza-Silva, AC Carvalho… - Pathogens, 2023 - mdpi.com
Chagas disease, a neglected disease caused by the protozoan Trypanosoma cruzi, is
endemic in 21 Latin American countries, affecting 6–8 million people. Increasing numbers of …
endemic in 21 Latin American countries, affecting 6–8 million people. Increasing numbers of …
Resident human dermal γδT-cells operate as stress-sentinels: lessons from the hair follicle
Y Uchida, J Gherardini, K Pappelbaum, J Chéret… - Journal of …, 2021 - Elsevier
Murine γδT-cells have stress-surveillance functions and are implicated in autoimmunity. Yet,
whether human γδT-cells are also stress sentinels and directly promote autoimmune …
whether human γδT-cells are also stress sentinels and directly promote autoimmune …
T-cell subpopulations exhibit distinct recruitment potential, immunoregulatory profile and functional characteristics in Chagas versus idiopathic dilated …
EGA Neves, CC Koh, TG Souza-Silva… - Frontiers in …, 2022 - frontiersin.org
Chronic Chagas cardiomyopathy (CCC) is one of the deadliest cardiomyopathies known
and the most severe manifestation of Chagas disease, which is caused by infection with the …
and the most severe manifestation of Chagas disease, which is caused by infection with the …
Activation of Human CD11b+ B1 B-Cells by Trypanosoma cruzi-Derived Proteins Is Associated With Protective Immune Response in Human Chagas Disease
B-cells mediate humoral adaptive immune response via the production of antibodies and
cytokines, and by inducing T-cell activation. These functions can be attributed to distinct B …
cytokines, and by inducing T-cell activation. These functions can be attributed to distinct B …
Chagas disease: comments on the 2018 PAHO Guidelines for diagnosis and management
FF Norman, R López-Vélez - Journal of travel medicine, 2019 - academic.oup.com
Abstract Background Chagas disease, or American trypanosomiasis, is a protozoan
infectious disease endemic throughout most of the Americas, caused by the trypanosome …
infectious disease endemic throughout most of the Americas, caused by the trypanosome …
Distinct CD4−CD8− (Double-Negative) Memory T-Cell Subpopulations Are Associated With Indeterminate and Cardiac Clinical Forms of Chagas Disease
CD4− CD8−(double-negative, DN) T cells are critical orchestrators of the cytokine network
associated with the pathogenic inflammatory response in one of the deadliest …
associated with the pathogenic inflammatory response in one of the deadliest …
Systemic cytokines, chemokines and growth factors reveal specific and shared immunological characteristics in infectious cardiomyopathies
Heart disease is a major cause of death worldwide. Chronic Chagas cardiomyopathy (CCC)
caused by infection with Trypanosoma cruzi leading to high mortality in adults, and …
caused by infection with Trypanosoma cruzi leading to high mortality in adults, and …
Blocking activation of CD4− CD8− T cells modulates their cytotoxic potential and decreases the expression of inflammatory and chemotactic receptors
EGA Neves, CC Koh, PPD Lucinda, TG Souza-Silva… - Clinical …, 2023 - Elsevier
Abstract CD4− CD8−(double negative–DN) T cells represent a small fraction of circulating T
lymphocytes but are a major source of pro-inflammatory cytokines in patients with infectious …
lymphocytes but are a major source of pro-inflammatory cytokines in patients with infectious …