Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

The use of magnetism in medicine has changed dramatically since its first application by the
ancient Greeks in 624 BC. Now, by leveraging magnetic nanoparticles, investigators have …

Gadolinium-based contrast agents (GBCAs) have revolutionized MRI, enabling physicians
to obtain crucial life-saving medical information that often cannot be obtained with other …

Hyperthermia, though by itself generally non-curative for cancer, can significantly increase
the efficacy of radiation therapy, as demonstrated by in vitro, in vivo, and clinical results. Its …

Mn (II) has several favorable physicochemical characteristics and a good toxicity profile,
which makes it a viable alternative to the Gd (III)-based MRI contrast agents currently used in …

Gadolinium-based contrast agents (GBCAs) are widely used with clinical magnetic
resonance imaging (MRI), and 10 s of millions of doses of GBCAs are administered annually …

Liver fibrogenesis is accompanied by upregulation of lysyl oxidase enzymes, which catalyze
oxidation of lysine ε-amino groups on the extracellular matrix proteins to form the aldehyde …

Radiometals play an important role in the diagnosis of physiological processes in vivo by
means of imaging technologies, but also increasingly contribute to the treatment of diseases …

Manganese‐based contrast agents (MnCAs) have emerged as suitable alternatives to
gadolinium‐based contrast agents (GdCAs). However, due to their kinetic lability and …

The presence of multiple oxidation and spin states of first-row transition-metal complexes
facilitates the development of switchable MRI probes. Redox-responsive probes capitalize …