Antimicrobial peptides: Promising alternatives in the post feeding antibiotic era

J Wang, X Dou, J Song, Y Lyu, X Zhu… - Medicinal research …, 2019 - Wiley Online Library
Antimicrobial peptides (AMPs), critical components of the innate immune system, are widely
distributed throughout the animal and plant kingdoms. They can protect against a broad …

How melittin inserts into cell membrane: conformational changes, inter-peptide cooperation, and disturbance on the membrane

J Hong, X Lu, Z Deng, S **ao, B Yuan, K Yang - Molecules, 2019 - mdpi.com
Antimicrobial peptides (AMPs), as a key component of the immune defense systems of
organisms, are a promising solution to the serious threat of drug-resistant bacteria to public …

Opening of the blood-brain barrier tight junction due to shock wave induced bubble collapse: a molecular dynamics simulation study

A Goliaei, U Adhikari, ML Berkowitz - ACS chemical neuroscience, 2015 - ACS Publications
Passage of a shock wave across living organisms may produce bubbles in the blood
vessels and capillaries. It was suggested that collapse of these bubbles imposed by an …

[HTML][HTML] Membrane Activity of Melittin and Magainin-I at Low Peptide-to-Lipid Ratio: Different Types of Pores and Translocation Mechanisms

MV Volovik, OV Batishchev - Biomolecules, 2024 - mdpi.com
Antimicrobial peptides (AMPs) are believed to be a prominent alternative to the common
antibiotics. However, despite decades of research, there are still no good clinical examples …

Membrane perturbation of fullerene and graphene oxide distinguished by pore-forming peptide melittin

C Zhang, Y Ge, X Lu, Z Chen, J Liu, M Zhang, K Yang… - Carbon, 2021 - Elsevier
Carbon nanomaterials such as fullerenes (C 60) and graphene oxide (GO) are considered
as promising candidates for diverse applications in biotechnology and biomedicine …

Organizations of melittin peptides after spontaneous penetration into cell membranes

L Sun, S Wang, F Tian, H Zhu, L Dai - Biophysical Journal, 2022 - cell.com
The antimicrobial peptide, melittin, is a potential next-generation antibiotic because melittin
can spontaneously form pores in bacterial cell membranes and cause cytoplasm leakage …

Magainin-H2 effects on the permeabilization and mechanical properties of giant unilamellar vesicles

A Mescola, N Marín-Medina, G Ragazzini… - Journal of Colloid and …, 2019 - Elsevier
Among the potential novel therapeutics to treat bacterial infections, antimicrobial peptides
(AMPs) are a very promising substitute due to their broad-spectrum activity and rapid …

Membrane stress profiles from self-consistent field theory

CL Ting, M Müller - The Journal of Chemical Physics, 2017 - pubs.aip.org
Using self-consistent field theory (SCFT), we develop an accurate, local expression for the
stress profiles in membranes and soft matter interfaces, in general. The bond stresses are …

[HTML][HTML] Effects of the peptide Magainin H2 on Supported Lipid Bilayers studied by different biophysical techniques

N Marín-Medina, A Mescola, A Alessandrini - Biochimica et Biophysica Acta …, 2018 - Elsevier
Given the increasing trend in bacterial antibiotic resistance, research on antimicrobial
peptides and their mechanisms of action has become of huge relevance in the last years …

Residue-specialized membrane poration kinetics of melittin and its variants: insight from mechanistic landscapes

ZX Deng, JL Li, B Yuan, K Yang - Communications in Theoretical …, 2019 - iopscience.iop.org
Pore-forming peptides have promising potentials for biomedical uses due to their ability to
permeabilize cell membranes. However, to molecularly engineer them for practical …