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Signaling pathways in rheumatoid arthritis: implications for targeted therapy
Q Ding, W Hu, R Wang, Q Yang, M Zhu, M Li… - Signal transduction and …, 2023 - nature.com
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …
progression leads to joint deformity and associated loss of function, which significantly …
Traditional herbal medicine: Therapeutic potential in rheumatoid arthritis
Y Wang, S Chen, K Du, C Liang, S Wang… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Rheumatoid arthritis (RA) is a chronic inflammatory
autoimmune disease influenced by diverse endogenous and exogenous factors. It is …
autoimmune disease influenced by diverse endogenous and exogenous factors. It is …
[HTML][HTML] Pathogenic role of immune cells in rheumatoid arthritis: implications in clinical treatment and biomarker development
HY Yap, SZY Tee, MMT Wong, SK Chow, SC Peh… - Cells, 2018 - mdpi.com
Rheumatoid arthritis (RA) is a chronic, autoimmune, systemic, inflammatory disorder that
affects synovial joints, both small and large joints, in a symmetric pattern. This disorder …
affects synovial joints, both small and large joints, in a symmetric pattern. This disorder …
Selective JAKinibs: prospects in inflammatory and autoimmune diseases
AT Virtanen, T Haikarainen, J Raivola, O Silvennoinen - BioDrugs, 2019 - Springer
Cytokines, many of which signal through the JAK–STAT (Janus kinase–Signal Transducers
and Activators of Transcription) pathway, play a central role in the pathogenesis of …
and Activators of Transcription) pathway, play a central role in the pathogenesis of …
Route to rheumatoid arthritis by macrophage-derived microvesicle-coated nanoparticles
The targeted delivery of therapeutics to sites of rheumatoid arthritis (RA) has been a long-
standing challenge. Inspired by the intrinsic inflammation-targeting capacity of …
standing challenge. Inspired by the intrinsic inflammation-targeting capacity of …
Recent advances in nanoparticle-based drug delivery systems for rheumatoid arthritis treatment
Nanotechnology has increasingly emerged as a promising tool for exploring new
approaches, from treating complex conditions to early detection of the onset of multiple …
approaches, from treating complex conditions to early detection of the onset of multiple …
[HTML][HTML] Targeting probiotics in rheumatoid arthritis
SG Bungau, T Behl, A Singh, A Sehgal, S Singh… - Nutrients, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a progressive inflammatory disorder characterized by swollen
joints, discomfort, tightness, bone degeneration and frailty. Genetic, agamogenetic and sex …
joints, discomfort, tightness, bone degeneration and frailty. Genetic, agamogenetic and sex …
Inhibition of MMPs and ADAM/ADAMTS
CJ Malemud - Biochemical pharmacology, 2019 - Elsevier
Abstract Matrix metalloproteinases (MMPs), A Disintegrin and Metalloproteinase (ADAM)
and A Disintegrin and Metalloproteinase with Thrombospondin Motif (ADAMTS) are zinc …
and A Disintegrin and Metalloproteinase with Thrombospondin Motif (ADAMTS) are zinc …
Intake of ω-3 polyunsaturated fatty acids in patients with rheumatoid arthritis: A systematic review and meta-analysis
Objectives Rheumatoid arthritis (RA) is a chronic, autoimmune inflammatory disease of
multiple joints that puts the patient at high risk for develo** cardiovascular diseases …
multiple joints that puts the patient at high risk for develo** cardiovascular diseases …
A review of hyaluronic acid-based therapeutics for the treatment and management of arthritis
Hyaluronic acid (HA), a biodegradable, biocompatible and non-immunogenic therapeutic
polymer is a key component of the cartilage extracellular matrix (ECM) and has been widely …
polymer is a key component of the cartilage extracellular matrix (ECM) and has been widely …