[HTML][HTML] Long COVID or post-acute sequelae of COVID-19 (PASC): an overview of biological factors that may contribute to persistent symptoms

AD Proal, MB VanElzakker - Frontiers in microbiology, 2021 - frontiersin.org
The novel virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused
a pandemic of coronavirus disease 2019 (COVID-19). Across the globe, a subset of patients …

[HTML][HTML] The central nervous system and the gut microbiome

G Sharon, TR Sampson, DH Geschwind… - Cell, 2016 - cell.com
Neurodevelopment is a complex process governed by both intrinsic and extrinsic signals.
While historically studied by researching the brain, inputs from the periphery impact many …

Metagenome-wide association of gut microbiome features for schizophrenia

F Zhu, Y Ju, W Wang, Q Wang, R Guo, Q Ma… - Nature …, 2020 - nature.com
Evidence is mounting that the gut-brain axis plays an important role in mental diseases
fueling mechanistic investigations to provide a basis for future targeted interventions …

The mutual interplay of gut microbiota, diet and human disease

P Illiano, R Brambilla, C Parolini - The FEBS journal, 2020 - Wiley Online Library
The intestinal milieu harbours the gut microbiota, consisting of a complex community of
bacteria, archaea, fungi, viruses and protozoans that bring to the host organism an …

[HTML][HTML] The healthy human blood microbiome: fact or fiction?

DJ Castillo, RF Rifkin, DA Cowan… - Frontiers in cellular and …, 2019 - frontiersin.org
The blood that flows perpetually through our veins and arteries performs numerous functions
essential to our survival. Besides distributing oxygen, this vast circulatory system facilitates …

The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Understanding the role of the gut microbiome in brain development and its association with neurodevelopmental psychiatric disorders

S Dash, YA Syed, MR Khan - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
The gut microbiome has a tremendous influence on human physiology, including the
nervous system. During fetal development, the initial colonization of the microbiome …

Antipsychotics, metabolic adverse effects, and cognitive function in schizophrenia

NE MacKenzie, C Kowalchuk, SM Agarwal… - Frontiers in …, 2018 - frontiersin.org
Cognitive impairment is a core symptom domain of schizophrenia. The effect of
antipsychotics, the cornerstone of treatment in schizophrenia, on this domain is not fully …

The role of cytokines in the pathogenesis of schizophrenia

B Dawidowski, A Górniak, P Podwalski… - Journal of Clinical …, 2021 - mdpi.com
Schizophrenia is a chronic mental illness of unknown etiology. A growing and compelling
body of evidence implicates immunologic dysfunction as the key element in its …

Multi-method characterization of the human circulating microbiome

E Whittle, MO Leonard, R Harrison, TW Gant… - Frontiers in …, 2019 - frontiersin.org
The term microbiome describes the genetic material encoding the various microbial
populations that inhabit our body. Whilst colonization of various body niches (eg, the gut) by …