Epicardial adipose tissue may mediate deleterious effects of obesity and inflammation on the myocardium
M Packer - Journal of the American College of Cardiology, 2018 - jacc.org
Epicardial adipose tissue has unique properties that distinguish it from other depots of
visceral fat. Rather than having distinct boundaries, the epicardium shares an unobstructed …
visceral fat. Rather than having distinct boundaries, the epicardium shares an unobstructed …
Obesity-induced changes in adipose tissue microenvironment and their impact on cardiovascular disease
Obesity is causally linked with the development of cardiovascular disorders. Accumulating
evidence indicates that cardiovascular disease is the collateral damage of obesity-driven …
evidence indicates that cardiovascular disease is the collateral damage of obesity-driven …
Epicardial adipose tissue: anatomic, biomolecular and clinical relationships with the heart
A growing amount of evidence suggests that regional fat distribution plays an important part
in the development of an unfavorable metabolic and cardiovascular risk profile. Epicardial …
in the development of an unfavorable metabolic and cardiovascular risk profile. Epicardial …
Pericardial fat, visceral abdominal fat, cardiovascular disease risk factors, and vascular calcification in a community-based sample: the Framingham Heart Study
Background—Pericardial fat may be an important mediator of metabolic risk. Correlations
with cardiovascular disease risk factors and vascular calcification in a community-based …
with cardiovascular disease risk factors and vascular calcification in a community-based …
Guidelines for the measurement of vascular function and structure in isolated arteries and veins
The measurement of vascular function in isolated vessels has revealed important insights
into the structural, functional, and biomechanical features of the normal and diseased …
into the structural, functional, and biomechanical features of the normal and diseased …
The adipose organ
S Cinti - Adipose tissue and adipokines in health and disease, 2007 - Springer
Mammals are provided with an organ that has been neglected by scientists in the past: the
adipose organ. This organ is formed by a series of well-defined depots mainly located at two …
adipose organ. This organ is formed by a series of well-defined depots mainly located at two …
Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue
SN Saxton, BJ Clark, SB Withers… - Physiological …, 2019 - journals.physiology.org
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …
Adipose tissue distribution and morphology play a key role in determining the degree of …
Perivascular adipose tissue inflammation in vascular disease
R Nosalski, TJ Guzik - British journal of pharmacology, 2017 - Wiley Online Library
Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of
cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in …
cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in …
Local inflammation and hypoxia abolish the protective anticontractile properties of perivascular fat in obese patients
Background—Inflammation in adipose tissue has been implicated in vascular dysfunction,
but the local mechanisms by which this occurs are unknown. Methods and Results—Small …
but the local mechanisms by which this occurs are unknown. Methods and Results—Small …
Newly identified regulators of ovarian folliculogenesis and ovulation
E Gershon, N Dekel - International journal of molecular sciences, 2020 - mdpi.com
Each follicle represents the basic functional unit of the ovary. From its very initial stage of
development, the follicle consists of an oocyte surrounded by somatic cells. The oocyte …
development, the follicle consists of an oocyte surrounded by somatic cells. The oocyte …