Pathogenesis of Helicobacter pylori infection

M Denic, E Touati, H De Reuse - Helicobacter, 2020 - Wiley Online Library
The original strategies developed by Helicobacter pylori to persistently colonise its host and
to deregulate its cellular functions make this bacterium an outstanding model to study host …

Bacterial DNA methyltransferase: A key to the epigenetic world with lessons learned from proteobacteria

Q Gao, S Lu, Y Wang, L He, M Wang, R Jia… - Frontiers in …, 2023 - frontiersin.org
Epigenetics modulates expression levels of various important genes in both prokaryotes and
eukaryotes. These epigenetic traits are heritable without any change in genetic DNA …

Evolved to vary: genome and epigenome variation in the human pathogen Helicobacter pylori

F Ailloud, I Estibariz, S Suerbaum - FEMS Microbiology Reviews, 2021 - academic.oup.com
Helicobacter pylori is a Gram-negative, spiral shaped bacterium that selectively and
chronically infects the gastric mucosa of humans. The clinical course of this infection can …

The Helicobacter pylori methylome is acid-responsive due to regulation by the two-component system ArsRS and the type I DNA methyltransferase HsdM1 (HP0463)

EH Zimmerman, EL Ramsey, KE Hunter… - Journal of …, 2024 - Am Soc Microbiol
In addition to its role in genome protection, DNA methylation can regulate gene expression.
In this study, we characterized the impact of acidity, phase variation, and the ArsRS TCS on …

Characterisation of RNA guanine-7 methyltransferase (RNMT) using a small molecule approach

LA Pearson, AP Petit, C Mendoza-Martinez… - Biochemical …, 2025 - portlandpress.com
The maturation of the RNA cap involving guanosine N-7 methylation, catalyzed by the
HsRNMT (RNA guanine-7 methyltransferase)-RAM (RNA guanine-N7 methyltransferase …

Chelerythrine, a new benzo [c] phenanthridine based converter of alternate DNA structure into conventional one: A spectroscopic exploration

S Bhuiya, A Datta, L Paul, S Das - Journal of Molecular Structure, 2024 - Elsevier
Association of different polymprphic forms of DNA having alternating GC sequences with the
alkaloid Chelerythrine Chloride (CHL) was probed by using UV absorption and circular …

A Theory of Biodiversity and Gene Evolution

H El-Nabi, E Sobhy - Journal of Bioscience and Applied Research, 2020 - journals.ekb.eg
The statement of theory:{Evolution of organisms and biodiversity depends mainly on gene
evolution through the appearance of novel genes. Biodiversity results from the DNA …