Copper complexes as artificial DNA metallonucleases: from Sigman's reagent to next generation anti-cancer agent?
TJP McGivern, S Afsharpour, CJ Marmion - Inorganica Chimica Acta, 2018 - Elsevier
Platinum drugs continue to dominate medical oncology treatments but they have
shortcomings associated with their use including dose-limiting toxic side effects and …
shortcomings associated with their use including dose-limiting toxic side effects and …
Design, synthesis, characterization, cytotoxicity, molecular docking and analysis of binding interactions of novel acetylacetonatopalladium (II) alanine and valine …
A Heydari, H Mansouri-Torshizi - RSC advances, 2016 - pubs.rsc.org
To enhance the development of potential anti-tumor agents, a pair of new, water-soluble and
neutral acetylacetonatopalladium (II) complexes with alanine and valine amino acids have …
neutral acetylacetonatopalladium (II) complexes with alanine and valine amino acids have …
Binucleating hydrazonic ligands and their μ-hydroxodicopper (II) complexes as promising structural motifs for enhanced antitumor activity
JP Rada, BSM Bastos, L Anselmino… - Inorganic …, 2019 - ACS Publications
Very few inorganic antineoplastic drugs have entered the clinic in the last decades, mainly
because of toxicity issues. Because copper is an essential trace element of ubiquitous …
because of toxicity issues. Because copper is an essential trace element of ubiquitous …
[HTML][HTML] Spectroscopic investigations on partial intercalative binding behaviour of terpyridine based copper (II) complexes with DNA
Copper based metal complexes have been studied extensively towards DNA interaction
aspects, the possible interactions being at the major or minor grooves, intercalation between …
aspects, the possible interactions being at the major or minor grooves, intercalation between …
Synthesis, characterization and biological applications of substituted pyrazolone core based platinum (II) organometallic compounds
MV Lunagariya, KP Thakor, DN Kanthecha… - Journal of Organometallic …, 2018 - Elsevier
New series of organometallic platinum (II) compounds (I-VI) containing the 2-phenyl-5-
methyl pyrazole-3-one derivatives ligands (L 1-L 6) were synthesized and characterized by …
methyl pyrazole-3-one derivatives ligands (L 1-L 6) were synthesized and characterized by …
Synthesis, characterization, cytotoxicity, DNA binding and computational studies of an anionic palladium (II) complex derived from 8-hydroxyquinoline and 1, 1 …
Abstract A novel 1, 1-cyclobutanedicarboxylato-8-hydroxyquinolinatopalladate (II), Na [Pd (8-
QO)(cbdca)](8-QO= 8-hydroxyquinoline and cbdca= 1, 1-cyclobutanedicarboxylate) has …
QO)(cbdca)](8-QO= 8-hydroxyquinoline and cbdca= 1, 1-cyclobutanedicarboxylate) has …
Design, synthesis, in vitro anticancer, antioxidant and antibacterial activity; DNA/BSA binding, photoleavage and docking studies of Cu(II) ternary metal complexes
Three mononuclear, mixed ligand ternary Cu (II) complexes of 3-((Z)-1-(2-
hydroxyphenylimino) ethyl)-4-hydroxy-6-methyl-2H-pyran-2-one (HEHMP) viz;[Cu …
hydroxyphenylimino) ethyl)-4-hydroxy-6-methyl-2H-pyran-2-one (HEHMP) viz;[Cu …
[HTML][HTML] Structure dependent selective efficacy of pyridine and pyrrole based Cu (II) Schiff base complexes towards in vitro cytotoxicity, apoptosis and DNA-bases …
This work highlights a systematic and comparative study of the structure-dependent
influence of a series of biologically active Cu (II) Schiff base complexes (CSCs) on their in …
influence of a series of biologically active Cu (II) Schiff base complexes (CSCs) on their in …
Synthesis and crystal structure of bicopper (II) complexes: The influence of bridging ligands on DNA/BSA binding behaviors and in vitro antitumor activity
XW Li, XH Zhao, YT Li, ZY Wu - Inorganica Chimica Acta, 2019 - Elsevier
Two new μ-oxamide or μ-oxamate bridged bicopper (II) complexes,[Cu 2 (mapox)(bpy)
2](ClO 4) 2 (1) and Cu 2 (mapoa)(CH 3 OH)(bpy) 2 (pic) 2· 0.5 H 2 O (2)(H 2 mapox= N, N …
2](ClO 4) 2 (1) and Cu 2 (mapoa)(CH 3 OH)(bpy) 2 (pic) 2· 0.5 H 2 O (2)(H 2 mapox= N, N …
Design, Synthesis, In vitro and In silico Alpha Glucosidase and Lipoxygenase Inhibition Studies of Copper(II) Oxamide Complexes
Metal complexes have pivotal applications in catalysis, photochemistry, and biological
systems. Due to their unique chemical properties, metal complexes occupy a coveted place …
systems. Due to their unique chemical properties, metal complexes occupy a coveted place …