The extreme toxicity and ready accessibility of nerve agents and phosgene has caused an
increase in the demand to develop effective systems for the detection of these substances …

Irreversible inhibition of acetylcholinesterase (AChE) by organophosphates leads to many
failures in living organism and ultimately in death. Organophosphorus compounds …

An ESIPT based fluorescent probe, containing a hydroxyphenyl-benzothiazole fluorophore
and an oxime reaction site, serves as a selective probe for a nerve gas mimic, diethyl …

A new class of amidine− oxime reactivators of organophosphate (OP)-inhibited
cholinesterases (ChE) were designed, synthesized, and tested. These compounds …

A new class of amidine-oxime reactivators of organophosphate (OP)-inhibited
cholinesterases (ChE) was synthesized and tested in vitro and in vivo. Compared with 2 …

Ellman's assay is the most commonly used method to measure cholinesterase activity. It is
cheap, fast, and reliable, but it has limitations when used for biological samples. The …

In recent year syria rejuvenate interest in chemical warfare agents (CWAs) for terrorist
attacks. Nerve agents are the most scandalous chemicals and can cause death of a person …

The use of cosolvents to solubilize compounds under investigation while having minimal
effects on enzyme activity is an important component in many biochemical studies …

Chromogenic probe with oxidized bis-indolyl scaffold has been synthesized for the detection
of a nerve gas mimicking agent, DCNP (diethyl cyanophosphonate) at pH 8.0 in water. The …

The G‐class nerve agents, which include sarin, soman, and cyclosarin, react readily with
nucleophilic reagents to produce fluoride. Thus, a chemosensing protocol has been …