[HTML][HTML] A 3′ external transcribed spacer in a tRNA transcript acts as a sponge for small RNAs to prevent transcriptional noise
D Lalaouna, MC Carrier, S Semsey, JS Brouard… - Molecular cell, 2015 - cell.com
During ribosomal and transfer RNA maturation, external transcribed spacer (ETS) and
internal transcribed spacer (ITS) sequences are excised and, as non-functional by-products …
internal transcribed spacer (ITS) sequences are excised and, as non-functional by-products …
Transcriptome data are insufficient to control false discoveries in regulatory network inference
Inference of causal transcriptional regulatory networks (TRNs) from transcriptomic data
suffers notoriously from false positives. Approaches to control the false discovery rate (FDR) …
suffers notoriously from false positives. Approaches to control the false discovery rate (FDR) …
The role of integration host factor in Escherichia coli persister formation
SE Nicolau, K Lewis - MBio, 2022 - Am Soc Microbiol
Persisters represent a small subpopulation of cells that are tolerant of killing by antibiotics
and are implicated in the recalcitrance of chronic infections to antibiotic therapy. One …
and are implicated in the recalcitrance of chronic infections to antibiotic therapy. One …
Stress response modulation: the key to survival of pathogenic and spoilage bacteria during poultry processing
The control of bacterial contaminants on meat is a key area of interest in the food industry.
Bacteria are exposed to a variety of stresses during broiler processing which challenge …
Bacteria are exposed to a variety of stresses during broiler processing which challenge …
Unveiling the genetic basis and metabolic rewiring behind the galactose-positive phenotype in a Streptococcus thermophilus mutant
H Hu, Q Peng, J Tai, W Lu, J Liu, T Dan - Microbiological research, 2024 - Elsevier
Streptococcus thermophilus (S. thermophilus) is a widely used starter culture in dairy
fermentation, but most strains are galactose-negative and only metabolize glucose from …
fermentation, but most strains are galactose-negative and only metabolize glucose from …
Escherichia coli σ70 promoters allow expression rate control at the cellular level in genome-integrated expression systems
A Schuller, M Cserjan-Puschmann, C Tauer… - Microbial Cell …, 2020 - Springer
Background The genome-integrated T7 expression system offers significant advantages, in
terms of productivity and product quality, even when expressing the gene of interest (GOI) …
terms of productivity and product quality, even when expressing the gene of interest (GOI) …
High-Level Production of Tyrosol with Noninduced Recombinant Escherichia coli by Metabolic Engineering
Tyrosol is a pharmacologically active phenolic compound widely used in the pharmaceutical
and chemical industries. Microbial fermentation has potential value as an environmentally …
and chemical industries. Microbial fermentation has potential value as an environmentally …
Quorum-sensing synchronization of synthetic toggle switches: A design based on monotone dynamical systems theory
EV Nikolaev, ED Sontag - PLoS computational biology, 2016 - journals.plos.org
Synthetic constructs in biotechnology, biocomputing, and modern gene therapy
interventions are often based on plasmids or transfected circuits which implement some form …
interventions are often based on plasmids or transfected circuits which implement some form …
Distribution of fitness effects of mutations obtained from a simple genetic regulatory network model
Beneficial and deleterious mutations change an organism's fitness but the distribution of
these mutational effects on fitness are unknown. Several experimental, theoretical, and …
these mutational effects on fitness are unknown. Several experimental, theoretical, and …
Evaluation of double expression system for co-expression and co-immobilization of flavonoid glucosylation cascade
A Matera, K Dulak, S Sordon, K Waśniewski… - Applied Microbiology …, 2022 - Springer
Glucosylation cascade consisting of Leloir glycosyltransferase and sucrose synthase with in
situ regeneration system of expensive and low available nucleotide sugars is a game …
situ regeneration system of expensive and low available nucleotide sugars is a game …