Contextual fear expression engages a complex set of interactions between ventromedial prefrontal cortex cholinergic, glutamatergic, nitrergic and cannabinergic …

DL Uliana, CRAF Diniz, LA da Silva… - …, 2023 - Elsevier
Rats re-exposed to an environment previously associated with the onset of shocks evoke a
set of conditioned defensive responses in preparation to an eventual flight or fight reaction …

Decoding the language of fear: Unveiling objective and subjective indicators in rodent models through a systematic review and meta-analysis

L Bao, J Rao, D Yu, B Zheng, B Yin - Neuroscience & Biobehavioral …, 2024 - Elsevier
While rodent models are vital for studying mental disorders, the underestimation of construct
validity of fear indicators has led to limitations in translating to effective clinical treatments …

The expression of contextual fear conditioning involves the dorsal hippocampus TRPV1 receptor interacting with the NMDA/NO/cGMP signalling pathway

GL Bertacchini, AB Sonego, SF Lisboa… - British Journal of …, 2025 - Wiley Online Library
Abstract Background and Purpose The dorsal hippocampus (dHIP) is pivotal for learning,
memory, and defensive responses. Transient receptor potential vanilloid type 1 (TRPV1) …

Chlorpyrifos intermittent exposure enhances cardiovascular but not behavioural responses to contextual fear conditioning in adult rats: Possible involvement of brain …

YFP Rosa, GG Noé, MGO Merlo, RR Calixto… - Behavioural Brain …, 2025 - Elsevier
Exposure to organophosphorus compounds (OPs) may cause psychiatric, neurologic,
biochemical, and cardiovascular abnormalities. Neurotoxicity of OP compounds is primarily …