Mechanisms of sound localization in mammals

B Grothe, M Pecka, D McAlpine - Physiological reviews, 2010 - journals.physiology.org
The ability to determine the location of a sound source is fundamental to hearing. However,
auditory space is not represented in any systematic manner on the basilar membrane of the …

Olivocochlear efferents: Their action, effects, measurement and uses, and the impact of the new conception of cochlear mechanical responses

JJ Guinan Jr - Hearing research, 2018 - Elsevier
The anatomy and physiology of olivocochlear (OC) efferents are reviewed. To help interpret
these, recent advances in cochlear mechanics are also reviewed. Lateral OC (LOC) …

Efferent feedback minimizes cochlear neuropathy from moderate noise exposure

SF Maison, H Usubuchi, MC Liberman - Journal of Neuroscience, 2013 - Soc Neuroscience
Although protective effects of the cochlea's efferent feedback pathways have been well
documented, prior work has focused on hair cell damage and cochlear threshold elevation …

Experience-dependent flexibility in a molecularly diverse central-to-peripheral auditory feedback system

MM Frank, AA Sitko, K Suthakar, LT Cadenas, M Hunt… - Elife, 2023 - elifesciences.org
Brainstem olivocochlear neurons (OCNs) modulate the earliest stages of auditory
processing through feedback projections to the cochlea and have been shown to influence …

Corticofugal modulation of peripheral auditory responses

G Terreros, PH Delano - Frontiers in systems neuroscience, 2015 - frontiersin.org
The auditory efferent system originates in the auditory cortex and projects to the medial
geniculate body (MGB), inferior colliculus (IC), cochlear nucleus (CN) and superior olivary …

Cochlear efferent innervation and function

JJ Guinan Jr - Current opinion in otolaryngology & head and neck …, 2010 - journals.lww.com
Techniques for measuring efferent effects using otoacoustic emissions are now well
developed and have promise in clinical applications ranging from predicting which patients …

Stochastic resonance controlled upregulation of internal noise after hearing loss as a putative cause of tinnitus-related neuronal hyperactivity

P Krauss, K Tziridis, C Metzner, A Schilling… - Frontiers in …, 2016 - frontiersin.org
Subjective tinnitus is generally assumed to be a consequence of hearing loss. In animal
studies it has been demonstrated that acoustic trauma induced cochlear damage can lead to …

Efferent feedback slows cochlear aging

MC Liberman, LD Liberman… - Journal of Neuroscience, 2014 - Soc Neuroscience
The inner ear receives two types of efferent feedback from the brainstem: one pathway
provides gain control on outer hair cells' contribution to cochlear amplification, and the other …

Olivocochlear efferent effects on perception and behavior

AM Lauer, SV Jimenez, PH Delano - Hearing research, 2022 - Elsevier
The role of the mammalian auditory olivocochlear efferent system in hearing has long been
the subject of debate. Its ability to protect against damaging noise exposure is clear, but …

Sound exposure dynamically induces dopamine synthesis in cholinergic LOC efferents for feedback to auditory nerve fibers

JS Wu, E Yi, M Manca, H Javaid, AM Lauer… - Elife, 2020 - elifesciences.org
Lateral olivocochlear (LOC) efferent neurons modulate auditory nerve fiber (ANF) activity
using a large repertoire of neurotransmitters, including dopamine (DA) and acetylcholine …