What is the Reason That the Pharmacological Future of Chemotherapeutics in the Treatment of Lung Cancer Could Be Most Closely Related to Nanostructures …
Over the course of several decades, anticancer treatment with chemotherapy drugs for lung
cancer has not changed significantly. Unfortunately, this treatment prolongs the patient's life …
cancer has not changed significantly. Unfortunately, this treatment prolongs the patient's life …
Lipophilicity as a central component of drug-like properties of chalchones and flavonoid derivatives
T Constantinescu, CN Lungu, I Lung - Molecules, 2019 - mdpi.com
Lipophilcity is an important physico-chemical parameter that influences membrane transport
and binding ability to action. Migration distance following complete elution of compounds …
and binding ability to action. Migration distance following complete elution of compounds …
The eigenproblem translated for alignment of molecules
L Jäntschi - Symmetry, 2019 - mdpi.com
Molecular conformation as a subproblem of the geometrical sha** of the molecules is
essential for the expression of biological activity. It is well known that from the series of all …
essential for the expression of biological activity. It is well known that from the series of all …
Insilico exploration C. koseri ATP synthase inhibitors by pharmacophore-based virtual screening, molecular docking and MD simulation
Citrobacter koseri is a gram-negative rod that causes infections in people who have
significant comorbidities and are immunocompromised. Antibiotic-resistant strains are …
significant comorbidities and are immunocompromised. Antibiotic-resistant strains are …
DFT Calculations of the structural, mechanical, and electronic properties of TiV alloy under high pressure
F Yu, Y Liu - Symmetry, 2019 - mdpi.com
A calculation program based on the density functional theory (DFT) is applied to study the
structural, mechanical, and electronic properties of TiV alloys with symmetric structure under …
structural, mechanical, and electronic properties of TiV alloys with symmetric structure under …
Docking of cisplatin on fullerene derivatives and some cube rhombellane functionalized homeomorphs
Cisplatin (cisPt) is one of the strongest anticancer agents with proven clinical activity against
a wide range of solid tumors. Its mode of action has been linked to its ability to crosslink with …
a wide range of solid tumors. Its mode of action has been linked to its ability to crosslink with …
Cheminformatics approach for identification of N-HyMenatPimeMelly as a novel potential ligand against RAS and renal chloride channel
Some angiotensin receptor (AR) blockers interfere with the renal chloride channel (ClC-K),
which plays an important role in urine concentration. Identifying ligands targeting this …
which plays an important role in urine concentration. Identifying ligands targeting this …
The immobilization of oxindole derivatives with use of cube rhombellane homeomorphs
A key aspect of modern drug research is the development of delivery methods that ensure
the possibility of implementing targeted therapy for a specific biological target. The use of …
the possibility of implementing targeted therapy for a specific biological target. The use of …
Postface for Applied Designs in Chemical Structures with High Symmetry
L Jäntschi - Symmetry, 2022 - mdpi.com
Probably the best example to start with with regard to structures with high symmetry (SHS) is
C60 fullerene (buckminsterfullerene)[1], a synthetic form of carbon resembling footballs [2] …
C60 fullerene (buckminsterfullerene)[1], a synthetic form of carbon resembling footballs [2] …
Docking of Platinum compounds on cube rhombellane functionalized homeomorphs
Platinum compounds are anti-cancer drugs and can bind to canonical purine bases, mainly
guanine, found within double helical DNA. Platinum compounds can be transferred directly …
guanine, found within double helical DNA. Platinum compounds can be transferred directly …