Alzheimer disease (AD) research faces challenges to successful enrollment, especially to
clinical trials and biomarker studies. Failure to recruit the planned number of participants in a …

Background Medical progress depends on the evaluation of new diagnostic and therapeutic
interventions within clinical trials. Clinical trial recruitment support systems (CTRSS) aim to …

In many healthcare organizations, comparative effectiveness research and quality
improvement (QI) investigations are hampered by a lack of access to data created as a …

Results of medical research studies are often contradictory or cannot be reproduced. One
reason is that there may not be enough patient subjects available for observation for a long …

Background: Social networking sites, particularly Facebook, are increasingly included in
contemporary smoking cessation interventions directed toward young adults. Little is known …

Electronic health records are increasingly being linked to DNA repositories and used as a
source of clinical information for genomic research. Privacy legislation in many jurisdictions …

This background paper addresses key issues related to involving people with dementia as
participants in research on care and services, including recruiting, research ethics, the …

Fast temporal query on large EHR-derived data sources presents an emerging big data
challenge, as this query modality is intractable using conventional strategies that have not …

Objective: Data from clinical care is increasingly being used for research purposes. The i2b2
platform has been introduced in some US research communities as a tool for data …

Objective The trade-off between the speed and simplicity of dictionary-based term
recognition and the richer linguistic information provided by more advanced natural …