Bacteria–phage coevolution as a driver of ecological and evolutionary processes in microbial communities
Bacteria–phage coevolution, the reciprocal evolution between bacterial hosts and the
phages that infect them, is an important driver of ecological and evolutionary processes in …
phages that infect them, is an important driver of ecological and evolutionary processes in …
Phage therapy as an alternative or complementary strategy to prevent and control biofilm-related infections
Highlights•Interaction of phages and biofilm cells depends on phage-host characteristics
and biofilm structure.•Biofilm features (eg matrix, cell metabolic state, resistant variants) …
and biofilm structure.•Biofilm features (eg matrix, cell metabolic state, resistant variants) …
Understanding the complex phage-host interactions in biofilm communities
Bacteriophages and bacterial biofilms are widely present in natural environments, a fact that
has accelerated the evolution of phages and their bacterial hosts in these particular niches …
has accelerated the evolution of phages and their bacterial hosts in these particular niches …
Phage–host interplay: examples from tailed phages and Gram-negative bacterial pathogens
Complex interactions between bacteriophages and their bacterial hosts play significant roles
in sha** the structure of environmental microbial communities, not only by genetic …
in sha** the structure of environmental microbial communities, not only by genetic …
Phage therapy with a focus on the human microbiota
Bacteriophages are viruses that infect bacteria. After their discovery in the early 1900s,
bacteriophages were a primary cure against infectious disease for almost 25 years, before …
bacteriophages were a primary cure against infectious disease for almost 25 years, before …
Designing P. aeruginosa synthetic phages with reduced genomes
In the era where antibiotic resistance is considered one of the major worldwide concerns,
bacteriophages have emerged as a promising therapeutic approach to deal with this …
bacteriophages have emerged as a promising therapeutic approach to deal with this …
Pharmacokinetics and pharmacodynamics of bacteriophage therapy: a review with a focus on multidrug-resistant Gram-negative bacterial infections
Despite the early recognition of their therapeutic potential and the current escalation of
multidrug-resistant (MDR) pathogens, the adoption of bacteriophages into mainstream …
multidrug-resistant (MDR) pathogens, the adoption of bacteriophages into mainstream …
The role of hyperparasitism in microbial pathogen ecology and evolution
Many micro-organisms employ a parasitic lifestyle and, through their antagonistic
interactions with host populations, have major impacts on human, agricultural and natural …
interactions with host populations, have major impacts on human, agricultural and natural …
Molecular mechanisms and drivers of pathogen emergence
Pathogen emergence (PE) is a complex phenomenon with major public health implications.
Over the past decades, numerous underlying mechanisms facilitating the emergence of …
Over the past decades, numerous underlying mechanisms facilitating the emergence of …
Formation of biofilms under phage predation: considerations concerning a biofilm increase
Bacteriophages are emerging as strong candidates for combating bacterial biofilms.
However, reports indicating that host populations can, in some cases, respond to phage …
However, reports indicating that host populations can, in some cases, respond to phage …