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Immune-based therapies in penile cancer
VB Joshi, PE Spiess, A Necchi, CA Pettaway… - Nature Reviews …, 2022 - nature.com
Penile cancer is a rare genitourinary malignancy that is associated with poor outcomes and
severely limited therapeutic options that are generally non-curative when used to treat …
severely limited therapeutic options that are generally non-curative when used to treat …
Immunotherapeutic approaches for the treatment of HPV-associated (pre-) cancer of the cervix, vulva and penis
TS Rafael, J Rotman, OR Brouwer… - Journal of Clinical …, 2022 - mdpi.com
Human papillomavirus (HPV) infection drives tumorigenesis in almost all cervical cancers
and a fraction of vulvar and penile cancers. Due to increasing incidence and low vaccination …
and a fraction of vulvar and penile cancers. Due to increasing incidence and low vaccination …
Atezolizumab with or without radiotherapy for advanced squamous cell carcinoma of the penis (the PERICLES study): a phase II trial
PURPOSE Patients with advanced penile squamous cell carcinoma have a poor prognosis
(21% 2-year overall survival [OS] from diagnosis). We assessed the activity of atezolizumab …
(21% 2-year overall survival [OS] from diagnosis). We assessed the activity of atezolizumab …
Safety and efficacy of immune checkpoint inhibitors in advanced penile cancer: report from the Global Society of Rare Genitourinary Tumors
Background Treatment options for penile squamous cell carcinoma are limited. We sought to
investigate clinical outcomes and safety profiles of patients with penile squamous cell …
investigate clinical outcomes and safety profiles of patients with penile squamous cell …
Assessment of PD-L1, TROP2, and nectin-4 expression in penile squamous cell carcinoma
Objectives There is an unmet need for therapeutically relevant biomarkers for advanced
penile squamous cell carcinoma (pSCC). Proposed immunohistochemistry (IHC)-based …
penile squamous cell carcinoma (pSCC). Proposed immunohistochemistry (IHC)-based …
Pembrolizumab for advanced penile cancer: a case series from a phase II basket trial
Background: Treatment options for unresectable, locally advanced or metastatic penile
squamous cell carcinoma (SCC) are limited. Previous studies have shown that 40–62% of …
squamous cell carcinoma (SCC) are limited. Previous studies have shown that 40–62% of …
Effective combinatorial immunotherapy for penile squamous cell carcinoma
Penile squamous cell carcinoma (PSCC) accounts for over 95% of penile malignancies and
causes significant mortality and morbidity in develo** countries. Molecular mechanisms …
causes significant mortality and morbidity in develo** countries. Molecular mechanisms …
The immune microenvironment in penile cancer and rationale for immunotherapy
ME Ahmed, S Falasiri, A Hajiran, J Chahoud… - Journal of clinical …, 2020 - mdpi.com
Penile cancer is an extremely rare malignancy that accounts for approximately 1% of cancer
deaths in the United States every year. While primary penile cancer can be managed …
deaths in the United States every year. While primary penile cancer can be managed …
Current management and future perspectives of penile cancer: An updated review
F Peyraud, C Allenet, M Gross-Goupil… - Cancer Treatment …, 2020 - Elsevier
Penile cancer (PeCa) is a rare disease worldwide, accounting for less than one percent of
all malignancies in men. It usually presents as a painless ulcer or lump on the head of the …
all malignancies in men. It usually presents as a painless ulcer or lump on the head of the …
PD-L1 and p16 expression in penile squamous cell carcinoma from an endemic region
MW De Bacco, GF Carvalhal, B MacGregor… - Clinical Genitourinary …, 2020 - Elsevier
Background Penile squamous cell carcinoma (PSCC) is a rare malignancy with higher
incidence in develo** countries. Treatment options include surgery, radiation therapy, and …
incidence in develo** countries. Treatment options include surgery, radiation therapy, and …