Although the biological functions of cell and tissue can be regulated by biochemical factors
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …

Stem cells respond to nanoscale surface features, with changes in cell growth and
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …

Thorough understanding of how to control cell behaviors including cell adhesion,
orientation, migration and differentiation on an artificial surface is critical in materials and life …

Enabling angiogenesis is critical for the success of tissue repair therapies and the fate of
tissue-engineered constructs. Although many biochemical signaling molecules have been …

This review reports the promising prospects of poly (lactic acid)(PLA) based nanostructured
materials considering two of their main potential uses, packaging and tissue engineering …

There is currently an unmet need for the supply of autologous, patient-specific stem cells for
regenerative therapies in the clinic. Mesenchymal stem cell differentiation can be driven by …

The current development of nanobiotechnologies requires a better understanding of cell–
surface interactions on the nanometre scale. Recently, advances in nanoscale patterning …

The interaction of cells and tissues with artificial materials designed for applications in
biotechnologies and in medicine is governed by the physical and chemical properties of the …

Current trends in clinical dental implant therapy include use of endosseous dental implant
surfaces embellished with nanoscale topographies. The goal of this review is to consider the …

As materials technology and the field of biomedical engineering advances, the role of
cellular mechanisms, in particular adhesive interactions with implantable devices, becomes …