Serum albumin: a multifaced enzyme

G De Simone, A di Masi, P Ascenzi - International Journal of Molecular …, 2021 - mdpi.com
Human serum albumin (HSA) is the most abundant protein in plasma, contributing actively to
oncotic pressure maintenance and fluid distribution between body compartments. HSA acts …

Human serum albumin: from bench to bedside

G Fanali, A Di Masi, V Trezza, M Marino… - Molecular aspects of …, 2012 - Elsevier
Human serum albumin (HSA), the most abundant protein in plasma, is a monomeric multi-
domain macromolecule, representing the main determinant of plasma oncotic pressure and …

Investigation of the interaction between berberine and human serum albumin

YJ Hu, Y Liu, XH **ao - Biomacromolecules, 2009 - ACS Publications
Berberine is an important traditional medicinal herb, which has been effectively used in the
treatment of dysentery, diarrhea, stomatitis, throat infections, and hepatitis in folk medicine …

Aggregation and binding-directed FRET modulation of conjugated polymer materials for selective and point-of-care monitoring of serum albumins

S Hussain, X Chen, C Wang, Y Hao, X Tian… - Analytical …, 2022 - ACS Publications
Nonspecific interactions of conjugated polymers (CPs) with various proteins prove to be a
major impediment for researchers when designing a suitable CP-based probe for the …

Site-selective binding of human serum albumin by palmatine: spectroscopic approach

YJ Hu, Y Ou-Yang, CM Dai, Y Liu, XH **ao - Biomacromolecules, 2010 - ACS Publications
In this study, fluorescence spectroscopy in combination with UV− vis absorption
spectroscopy and circular dichroism (CD) spectroscopy was employed to investigate the …

Allostery in a monomeric protein: the case of human serum albumin

P Ascenzi, M Fasano - Biophysical chemistry, 2010 - Elsevier
Human serum albumin (HSA), the most prominent protein in plasma, binds different classes
of ligands at multiple sites. The globular domain structural organization of monomeric HSA is …

Investigation of the interaction between amodiaquine and human serum albumin by fluorescence spectroscopy and molecular modeling

F Samari, M Shamsipur, B Hemmateenejad… - European journal of …, 2012 - Elsevier
The interaction of amodiaquine (AQ) with human serum albumin (HSA) has been studied by
fluorescence spectroscopy. Based on the sign and magnitude of the enthalpy and entropy …

Quantitation of albumin in serum using “turn-on” fluorescent probe with aggregation-enhanced emission characteristics

W Li, D Chen, H Wang, S Luo, L Dong… - … Applied Materials & …, 2015 - ACS Publications
An aggregation-enhanced emission active luminogen named as sodium 4, 4′ 4 ″-(3, 4-
diphenyl-1 H-pyrrole-1, 2, 5-triyl) tribenzoate (DP-TPPNa) with propeller construction was …

[HTML][HTML] Unraveling the versatility of human serum albumin–A comprehensive review of its biological significance and therapeutic potential

S Ashraf, H Qaiser, S Tariq, A Khalid… - Current Research in …, 2023 - Elsevier
Human serum albumin (HSA) is a multi-domain macromolecule with diverse ligand binding
capability because of its ability to allow allosteric modulation despite being a monomeric …

Heme-based catalytic properties of human serum albumin

P Ascenzi, A Di Masi, G Fanali, M Fasano - Cell death discovery, 2015 - nature.com
Abstract Human serum albumin (HSA):(i) controls the plasma oncotic pressure,(ii) modulates
fluid distribution between the body compartments,(iii) represents the depot and carrier of …